Blood borne viral infections among Danish Health Care Workers - Frequent blood exposure but low prevalence of infection

被引:24
作者
Fisker N. [1 ,5 ]
Mygind L.H. [2 ]
Krarup H.B. [3 ]
Licht D. [4 ]
Georgsen Jø. [1 ]
Christensen P.B. [1 ]
机构
[1] Department of Clinical Immunology, Odense University Hospital, Odense C
[2] Department of Internal Medicine, Odense University Hospital, Odense C
[3] Department of Clinical Chemistry, Aalborg Hospital, Aalborg
[4] Department of Clinical Microbiology, Odense University Hospital, Odense C
[5] Department of Clinical Immunology, Odense University Hospital, DK-5000 Odense C
关键词
Health care worker; Hepatitis B prevalence; Hepatitis B vaccination;
D O I
10.1023/B:EJEP.0000013397.51614.d4
中图分类号
学科分类号
摘要
Denmark is a country with low prevalence and incidence of blood borne viral infections. Among health care workers (HCWs) vaccination for hepatitis B is only offered to high-risk groups. The aims of this cross sectional survey were to determine the prevalence of hepatitis B, -C, and human immunodeficiency virus (HIV) among the staff at a Danish University hospital and to correlate this with risk factors for transmission. Additionally, we wanted to examine the current frequency of blood exposure, reporting habits and hepatitis B vaccination status in the staff. Of 1439 eligible hospital staffs included, 960 (67%) were HCWs. The overall human immunodeficiency virus (HIV)-, hepatitis C Virus (HCV)- and hepatitis B Virus (HBV)-prevalence was 0% (0/1439), 0.14% (2/1439) and 1.6% (23/1439), respectively. Twenty-three percent of HCWs were vaccinated against HBV. Age, blood transfusion and stay in endemic areas were associated independently to HBV infection as opposed to job-category, duration of employment, HBV vaccination status and blood exposure. Based on a 4-week recall period, the incidence of percutaneous blood exposure was 1.5/person-year. In conclusion the HIV and hepatitis prevalence was low despite frequent blood exposure and the principal risk factors were unrelated to work. Danish HCWs do not seem to be at increased risk of hepatitis B even though universal HBV vaccination has not been implemented.
引用
收藏
页码:61 / 67
页数:6
相关论文
共 24 条
[1]  
Gerberding J.L., Management of occupational exposures to blood-borne viruses, N Engl J Med, 332, pp. 444-451, (1995)
[2]  
Beltrami E.M., Williams I.T., Shapiro C.N., Chamberland M.E., Risk and management of blood-borne infections in health care workers, Clin Microbiol Rev, 13, pp. 385-407, (2000)
[3]  
Updated US Public Health Service guidelines for the management of occupational exposures to HBV, HCV, and HIV and recommendations for postexposure prophylaxis, MMWR Morb Mortal Wkly Rep, 50, RR-11, pp. 1-52, (2001)
[4]  
Christensen P.B., Titlestad I.L., Homburg K.M., Georgsen J., Kristensen T., Hepatitis B core antibodies in Danish blood donors: A surrogate marker of risk behaviour, Vox Sanguinis, 81, pp. 222-227, (2001)
[5]  
Iwarson S., Report from Working Group 3, Vaccine, 16, SUPPL. 1, (1998)
[6]  
Nelsing S., Wantzin P., Skot J., Et al., The seroprevalence of hepatitis B and C in hospitalized Danish patients, Scand J Infect Dis, 27, pp. 445-448, (1995)
[7]  
Christensen P.B., Epidemiology of hepatitis C, Ugeskr Laeger, 160, pp. 3529-3532, (1998)
[8]  
Hepatitisvejledning
[9]  
Krarup H.B., Drewes A.M., Madsen P.H., A quantitative HCV-PCR test for routine diagnostics, Scand J Clin Lab Invest, 58, pp. 415-422, (1998)
[10]  
Christenson B., Bottiger M., Grillner L., The prevalence of hepatitis B in Sweden