Obstructive sleep apnea syndrome: Effect of respiratory events and arousal on pulse wave amplitude measured by photoplethysmography in NREM sleep

被引：60

作者：

Haba-Rubio J. ^{[1
]}

Darbellay G. ^{[2
]}

Herrmann F.R. ^{[3
]}

Frey J.G. ^{[1
]}

Fernandes A. ^{[1
]}

Vesin J.M. ^{[2
]}

Thiran J.P. ^{[2
]}

Tschopp J.M. ^{[1
]}

机构：

[1] Sleep Laboratory, Centre Valaisan de Pneumologie

[2] Institute for Signal Processing Laboratory, Swiss Federal Institute of Technology, Lausanne

[3] Department of Rehabilitation, University Hospital, Geneva

来源：

Sleep and Breathing | 2005年 / 9卷 / 2期

关键词：

Arousal; Autonomic markers; O[!sub]2[!/sub] pulse wave amplitude; Obstructive sleep apnea;

D O I：

10.1007/s11325-005-0017-y

中图分类号：

学科分类号：

摘要：

The objective of the study is to evaluate changes in finger pulse wave amplitude (PWA), as measured by photoplethysmography, and heart rate (HR), related to obstructive respiratory events and associated arousals during sleep. We analyzed 1,431 respiratory events in NREM sleep from 12 patients according to (1) the type of event (apnea, hypopnea, upper airway resistance episode) and (2) the duration of the associated EEG arousal (>10, 3-10, <3 s). Obstructive respiratory events provoked a relative bradycardia and vasodilation followed by HR increase and vasoconstriction. Relative PWA changes were significantly greater than HR changes. These responses differed significantly according to EEG-arousal grades (time×arousal interaction, p<0.0001), with longer arousals producing greater responses, but not to the type of respiratory event (time×event interaction, p = ns). Obstructive respiratory events provoke HR and PWA changes, the magnitude seemingly related to the intensity of central nervous activation, with PWA changes greater than HR. PWA obtained from a simple pulse oxymeter might be a valuable method to evaluate sleep fragmentation in sleep breathing disorders. © Springer-Verlag 2005.

引用

页码：73 / 81

页数：8

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