A one-generation cluster of malignant mesothelioma within a family reveals exposure to asbestos-contaminated jute bags in Naples, Italy

被引：15

作者：

V. Ascoli

C. Carnovale-Scalzo

F. Nardi

C. Efrati

M. Menegozzo

机构：

[1] Anatomia Patologica, Dipto. di Med. Sperim. e Patologia, Univerisità La Sapienza, Roma

[2] Dipartimento di Medicina Clinica, Univerisità La Sapienza, Roma

[3] Sezione di Medicina del Lavoro, Dipto. di Medicina Sperimentale, II Università di Napoli, Napoli

[4] Anatomia Patologica, Dipto. di Med. Sperim. e Patologia, Univ. Degli Studie di Roma Sapineza, 00161 Rome

来源：

European Journal of Epidemiology | 2003年 / 18卷 / 2期

关键词：

Asbestos; Familial cancer; Italy; Jute; Malignant mesothelioma;

D O I：

10.1023/A:1023032214444

中图分类号：

学科分类号：

摘要：

Substantial evidence supports the role of asbestos in malignant mesothelioma. Clustering for this malignancy among relatives not only suggests genetic susceptibility as a relevant component but also provides a clue to investigate non-occupational sources of exposure. We identified five cases of malignant mesothelioma within one family with exposure to asbestos experienced during childhood, as 'next door' residents of a workshop recycling asbestos-contaminated jute sacks in Naples, Italy. This cluster discloses the health risk in the reuse of bags that previously had contained asbestos. Furthermore, it emphasizes the role of asbestos in the genetic-environmental interaction issue of malignant mesothelioma.

引用

页码：171 / 174

页数：3

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