Continuous surveillance of organochlorine compounds in human breast milk from 1972 to 1998 in Osaka, Japan

被引：77

作者：

Konishi Y. ^{[1
]}

Kuwabara K. ^{[1
]}

Hori S. ^{[1
]}

机构：

[1] Osaka Pref. Inst. of Public Health, Division of Food Hygiene, Osaka 537-0025, 1-3-69, Nakamichi, Higashinari-ku

来源：

Archives of Environmental Contamination and Toxicology | 2001年 / 40卷 / 4期

关键词：

Japan; Lactate; Chlorinate; Equilibrium State; PCBs;

D O I：

10.1007/s002440010212

中图分类号：

学科分类号：

摘要：

The presence of chlorinated organic compounds in breast milk of lactating, women living in Osaka Prefecture, Japan, has been followed since 1972. Following the highest concentration found ar the start of the measurements, contamination by polychlorinated biphenyls (PCBs) and organochlorine pesticides, such as β-HCH and DDT declined to about 3-13% of the peak levels by the mid-1970s and continued to decrease to low-level equilibrium states. This decline varies greatly with the chemical compound. In comparison with 1970s, when the contamination of breast milk was highest, the β-HCH level fell to about 3%, DDT to about 7%, and PCBs to about 13%, representative of different half-lives in the environment and the particular persistence of PCB. In the case of chlordane, a termite insecticide, more than 10 years have passed since its use was prohibited in Japan, but it continues to be found in human breast milk, although at a low level.

引用

页码：571 / 578

页数：7

共 32 条

[1]

Bletchly J.D., Polychlorinated biphenyls: Production, current use and possible rates of future disposal in OECD member countries, Proceedings of PCB-Seminar, pp. 343-372, (1984)

[2]

Cok I., Karakaya A.E., Afkham B.L., Burgaz S., Organochlorine pesticide contaminants in human milk samples collected in Tebriz (Iran), Bull Environ Contam Toxicol, 63, pp. 444-450, (1999)

[3]

Craan A.G., Haines D.A., Twenty-five years of surveillance for contaminants in human breast milk, Arch Environ Contam Toxicol, 35, pp. 702-710, (1998)

[4]

Czaja K., Ludwicki J.K., Goralczyk K., Strucinski P., Effect of changes in excretion of persistent organochlorine compounds with human breast milk on related exposure of breast-fed infants, Arch Environ Contam Toxicol, 36, pp. 498-503, (1999)

[5]

The regulation standard of PCB in the various food presented at Ministry of Health and Welfare, Japan

[6]

and acceptable daily intake (ADI) of residual pesticides, J Food Hyg Soc Japan, 35, pp. 105-110, (1994)

[7]

Goldberg E.D., Synthetic organohalides in the sea, Prec Roy Soc London Ser B, 189, pp. 277-289, (1975)

[8]

Hori S., Konishi Y., Kuwabara K., Decrease of PCDDs, PCDFs and Co-PCBs levels in human milk from Osaka (1973-1996), Organohal Comp, 44, pp. 141-144, (1999)

[9]

Konishi Y., Yakushiji T., Nishimune T., Kunita N., Continuous surveillance of organochlorine compounds in human milk (15th report). Focusing on the concentration of chlordane, Proc Osaka Pref Inst Publ Health (Ed. Food Sanitation), 20, pp. 35-42, (1989)

[10]

Konishi Y., Yakushiji T., Taguchi S., Nishimune T., Tanaka R., Increase of dietary chlordane intake in homes treated for termite control, J Food Hyg Soc Japan, 31, pp. 238-243, (1990)

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