Underweight is independently associated with mortality in post-operative and non-operative patients admitted to the intensive care unit: A retrospective study

被引：46

作者：

Finkielman J.D. ^{[1
]}

Gajic O. ^{[1
]}

Afessa B. ^{[1
]}

机构：

[1] Div. of Pulmonary/Critical Care Med., Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905

来源：

BMC Emergency Medicine | / 4卷 / 1期

关键词：

Body Mass Index; Intensive Care Unit; Intensive Care Unit Admission; Intensive Care Unit Length; Admission Source;

D O I：

10.1186/1471-227X-4-3

中图分类号：

学科分类号：

摘要：

Background. Low and high body mass index (BMI) have been recently shown to be associated with increased and decreased mortality after ICU admission, respectively. The objective of this study was to determine the impact of BMI on mortality and length of stay in patients admitted to the intensive care unit (ICU). Methods. In this retrospective cohort study, the Acute Physiology and Chronic Health Evaluation (APACHE) III database of patients admitted to the ICUs of a tertiary academic medical center, from January 1997 to September 2002, was crossed with a Hospital Rule-based Systems database to obtain the height and weight of the patients on admission to the ICU. The cohort was divided in post-operative and non-operative groups. We created the following five subgroups based on the BMI: <18.5, 18.5 to 24.9, 25 to 29.9, 30.0 to 39.9, ≥40.0 Kg/m2. A multiple logistic regression analysis was used to determine the independent impact of BMI on hospital mortality. The ICU length of stay ratio was defined as the ratio of the observed to the predicted LOS. P-value < 0.05 was considered significant. The 95% confidence interval (CI) was calculated for the odds ratio (OR). Results. BMI was available in 19,669 of the 21,790 patients in the APACHE III database; 11,215 (57%) of the patients were admitted post-operatively. BMI < 18.5 was associated with increased mortality in both post-operative (OR = 2.14, 95% CI, 1.39 to 3.28) and non-operative (OR= 1.51, 95% CI, 1.13 to 2.01) patients. Post-operative patients with a BMI between 30.0 to 39.9 had a lower mortality rate (OR = 0.68, 95% CI, 0.49 to 0.94). Post-operative patients with BMI <18.5 or BMI ≥40 had an ICU length of stay ratio significantly higher than patients with BMI between 18.5 to 24.9. The addition of BMI < 18.5 did not improve significantly the accuracy of our prognostic model in predicting hospital mortality. Conclusions. Low BMI is associated with higher mortality in both post- and non-operative patients admitted to the ICU. LOS is increased in post-operative patients with low and high BMIs. © 2004 Finkielman et al., licensee BioMed Central Ltd.

引用

页数：7

共 23 条

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