Demographic and intrapartum characteristics of term pregnancies with early-onset neonatal seizures

被引：1

作者：

Sorokin Y. ^{[1
,2
]}

Blackwell S. ^{[1
,2
]}

Reinke T. ^{[1
,2
]}

Kazzi N. ^{[1
,2
]}

Berman S. ^{[1
,2
]}

Bryant D. ^{[1
,2
]}

机构：

[1] Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Hutzel Hospital, Detroit Mediad Center, Wayne State University, Detroit MI

[2] Division of Neonatology, Department of Pediatrics, Hutzel Hospital, Detroit Mediad Center, Wayne State University, Detroit MI

来源：

Journal of Perinatology | 2001年 / 21卷 / 2期

关键词：

D O I：

10.1038/sj.jp.7200499

中图分类号：

学科分类号：

摘要：

OBJECTIVE: To compare the demographic and intrapartum factors of tenu pregnancies in which early-onset neonatal seizures developed with the characteristics of a large, unselected control population. STUDY DESIGN: Pregnancies delivered at term (gestational age≥37 weeks) in one birthing unit between 1984 and 1995 with a discharge diagnosis of neonatal seizures were identified. Maternal and neonatal charts of these patients were reviewed to confirm the diagnosis of early-onset seizure (EOS) which was defined as a clinical or EEG-diagnosed seizure within 72 hours of life. Demographic and intrapartum factors were compared between these EOS cases and all singleton term pregnancies delivered over the same time period in which there was no EOS. A regression model was then developed to determine factors predictive of EOS. RESULTS: Of 80,561 total deliveries during the 11-year study period, there were 64,340 control and 62 EOS (0.1%) deliveries. Regression modeling identified NICU admission, depressed 1- and 5-minute Apgar scores, and neonatal intubation as predictors of EOS, but not operative vaginal, vaginal breech, or cesarean delivery. CONCLUSION: Depressed condition at birth and/or the requirement for NICU care was the most important risk associated with early seizures in term infants. © 2001 Nature Publishing Group All rights reserved.

引用

页码：90 / 92

页数：2

共 8 条

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