Nutrition, growth, and body size in relation to insulin resistance and type 2 diabetes

被引：19

作者：

Chittaranjan S. Yajnik

机构：

[1] King Edward Memorial Hospital Research Center,Diabetes Unit

来源：

Current Diabetes Reports | 2003年 / 3卷 / 2期

关键词：

Birth Weight; Maternal Nutrition; Ponderal Index; Fetal Size; Adiposity Rebound;

D O I：

10.1007/s11892-003-0033-x

中图分类号：

学科分类号：

摘要：

Nutritional and genetic factors interact in the etiology of type 2 diabetes. Undernutrition followed by overnutrition increases adiposity and the risk of diabetes. The thrifty hypotheses suggest that the nutritional challenges could have happened thousands of year ago (thrifty gene selection) or during one's intrauterine life (thrifty phenotype). Current strategies for the prevention of diabetes are related to avoiding overnutrition.

引用

页码：108 / 114

页数：6

共 130 条

[1]

King H(1998)Global burden of diabetes, 1995-2025; prevalence, numerical estimates and projections Diabetes Care 21 1414-1431

[2]

Aubert RE(2001)High prevalence of diabetes and impaired glucose tolerance in India: National Urban Diabetes Survey Diabetologia 9 1094-1101

[3]

Herman WH(1991)Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians Lancet 337 971-973

[4]

Ramchandran A(1962)Diabetes mellitus: a “thrifty” genotype rendered detrimental by “progress”? Am J Human Genet 14 353-362

[5]

Snehalatha C(1992)Type 2 (non-insulin dependent) diabetes: the thrifty phenotype hypothesis Diabetologia 35 595-601

[6]

Kapur A(2001)The thrifty phenotype hypothesis Brit Med Bull 60 5-20

[7]

McKeigue PM(1988)Role of insulin resistance in human disease Diabetes 37 1595-1607

[8]

Shah B(1991)Fetal and infant growth and impaired glucose tolerance at age 64 BMJ 303 1019-1022

[9]

Marmot MG(1993)Type 2 (non-insulin dependent) diabetes mellitus, hypertension and hyperlipidemia (syndrome X): relation to reduced fetal growth Diabetologia 36 62-67

[10]

Neel JV(1998)Size at birth, maternal weight, and type 2 diabetes in South India Diabet Med 15 220-227

← 1 2 3 4 5 6 7 8 9 10 →