Cardiorenal syndrome in decompensated heart failure: prognostic and therapeutic implications.

被引:34
作者
Boerrigter G. [1 ]
Burnett Jr. J.C. [1 ]
机构
[1] Mayo Clinic, 200 First Street SW, Rochester, 55905, MN
基金
美国国家卫生研究院;
关键词
Natriuretic Peptide; Atrial Natriuretic Peptide; Loop Diuretic; Eplerenone; Tolvaptan;
D O I
10.1007/s11897-004-0020-9
中图分类号
学科分类号
摘要
Various lines of evidence implicate impaired renal function as an important prognostic indicator in patients with congestive heart failure (CHF). Conventional diuretics may aggravate renal dysfunction and can result in neurohumoral activation. Evolving new therapeutic strategies that enhance renal function include administration of B-type natriuretic peptide, adenosine and vasopressin antagonists, and ultrafiltration methods. Prospective studies are needed to evaluate whether these new renal-enhancing strategies will improve patient outcome in CHF.
引用
收藏
页码:113 / 120
页数:7
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