New developments in the neurobiology of borderline personality disorder

被引:34
作者
Bohus M. [1 ]
Schmahl C. [1 ]
Lieb K. [1 ]
机构
[1] Central Inst. Mental Health Mannheim, University of Heidelberg
关键词
Personality Disorder; Biol Psychiatry; Borderline Personality Disorder; Divalproex Sodium; Amygdala Volume;
D O I
10.1007/s11920-004-0038-4
中图分类号
学科分类号
摘要
Within the past several years, research on the clinical phenomena and neurobiology of borderline personality disorder has increased substantially. Borderline personality disorder is currently best thought of in terms of dimensions rather than as a categorical disorder. This article reviews the most recent findings on two of the core dimensions - affective dysregulation and impulsivity. Most of the neuropsychologic, physiologic, endocrinologic, and neuroimaging data support the theory that a dual brain pathology, affecting prefrontal and limbic circuits, may underlie this hyperarousal-dyscontrol syndrome. Copyright © 2004 by Current Science Inc.
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页码:43 / 50
页数:7
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