Epithelial tumours of the adult kidney

被引：15

作者：

R. Montironi

Gregor Mikuz

Ferran Algaba

Antonio Lopez-Beltran

Peter W. Hamilton

Constance Parkinson

机构：

[1] Institute of Pathological Anatomy,

[2] University of Ancona School of Medicine,undefined

[3] Regional Hospital,undefined

[4] I-60020 Torrette di Ancona,undefined

[5] Italy e-mail: r.montironi@popcsi.unian.it Tel.: +39-0715964830,undefined

[6] Fax: +39-071889985,undefined

[7] Department of Pathology,undefined

[8] University of Innsbruck,undefined

[9] Innsbruck,undefined

[10] Austria,undefined

[11] Department of Pathology,undefined

[12] Fundacio Puigvert,undefined

[13] Barcelona,undefined

[14] Spain,undefined

[15] Unit of Anatomic Pathology,undefined

[16] University Medical School,undefined

[17] Cordoba,undefined

[18] Spain,undefined

[19] Institute of Pathology,undefined

[20] The Queen’s University of Belfast,undefined

[21] Belfast,undefined

[22] Northern Ireland,undefined

[23] UK,undefined

[24] U.C.L. Hospitals Trust and Institute of Urology,undefined

[25] University College London Medical School,undefined

[26] London,undefined

[27] UK,undefined

来源：

Virchows Archiv | 1999年 / 434卷 / 4期

关键词：

Key words Renal parenchymal carcinoma; Renal cell carcinoma; Classification; Staging; Grading;

D O I：

10.1007/s004280050343

中图分类号：

学科分类号：

摘要：

The epithelial tumours of the adult kidney, in particular renal cell carcinoma (RCC), are a variety of neoplasms that can be classified by morphology and genotype. Although most are well characterised, typical and less typical tumour variants are recognised. There is evidence to indicate that stage is one of the most important prognostic factors, irrespective of tumour subtype. However, the appropriate handling of nephrectomy specimens is essential for accurate evaluation of diagnostic and prognostic factors in RCC. The problem of how to achieve more objective nuclear grading is still unresolved. The use of diagnostic decision support systems offers the possibility of a flexible approach to this problem, while still utilising morphological criteria. The histopathological analysis remains important, but new techniques of molecular and cell biology will be providing new tools of extraordinary power to sharpen the diagnosis and give it a biological interpretation.

引用

页码：281 / 290

页数：9