SUNCT and high nocturnal prolactin levels: Some new unusual characteristics

被引:14
作者
Bosco D. [1 ]
Labate A. [2 ]
Mungari P. [3 ]
Vero S. [4 ]
Fava A. [5 ]
机构
[1] Operative Unit of Neurology, S. Giovanni di Dio Hospital, I-88900 Crotone, Via Largo Bologna
[2] Department of Clinical Neurology, University Magna Graecia, Catanzaro
[3] Department of Emergency Medicine, S. Giovanni di Dio Hospital, Crotone
[4] Operative Unit of Radiology, S. Giovanni di Dio Hospital, Crotone
[5] Operative Unit of Endocrinology, University Magna Graecia, Catanzaro
关键词
Hyperprolactinaemia; Nocturnal headaches; SUNC; SUNCT and neuro-endocrine disorders;
D O I
10.1007/s10194-007-0370-2
中图分类号
学科分类号
摘要
SUNCT is a rare condition characterised by a short-lasting periorbital pain associated with autonomic symptoms and is usually unresponsive to pharmacological treatment. We report a case of SUNCT syndrome linked to a pituitary micro-adenoma, with only nocturnal attacks. The nocturnal levels of prolactin (PRL) were increased, while other hormonal, haematological, serological and biochemical investigations and levels of PRL did not reveal abnormal findings during the day-time. PRL serum secretion after thyrotropin-releasing hormone test was lower than nocturnal secretion, but not enough to induce severe attacks. We suggest that in our patient the rise of nocturnal levels of PRL could have a direct role in the worsening of this headache, perhaps secondarily to an altered regulation of the hypothalamic-hypophysial axis, however the actual influence of sleep and the interaction between all neurotransmitters and hormones needs to be clarified further. © Springer-Verlag Italia 2007.
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页码:114 / 118
页数:4
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