The nucleotide sequence of Saccharomyces cerevisiae chromosome VII

被引:44
作者
Tettelin H. [1 ]
Agostoni Carbone M.L. [2 ]
Albermann K. [3 ]
Albers M. [4 ]
Arroyo J. [5 ]
Backes U. [4 ]
Barreiros T. [6 ]
Bertani I. [7 ]
Bjourson A.J. [8 ]
Brückner M. [9 ]
Bruschi C.V. [7 ]
Carignani G. [10 ]
Castagnoli L. [11 ]
Cerdan E. [12 ]
Clemente M.L. [10 ]
Coblenz A. [4 ]
Coglievina M. [7 ]
Coissac E. [13 ]
Defoor E. [14 ]
Del Bino S. [1 ]
Delius H. [15 ]
Delneri D. [7 ]
De Wergifosse P. [1 ]
Dujon B. [16 ]
Durand P. [17 ]
Entian K.D. [18 ]
Eraso P. [19 ]
Escribano V. [19 ]
Fabiani L. [20 ]
Fartmann B. [21 ,34 ]
Feroli F. [10 ]
Feuermann M. [22 ]
Frontali L. [20 ]
García-Gonzalez M. [5 ,35 ]
García-Sáez M.I. [5 ]
Goffeau A. [1 ]
Guerreiro P. [6 ]
Hani J. [3 ]
Hansen M. [4 ]
Hebling U. [15 ]
Hernandez K. [23 ]
Heumann K. [3 ]
Hilger F. [17 ]
Hofmann B. [15 ]
Indge K.J. [24 ]
James C.M. [24 ]
Klima R. [7 ]
Kötter P. [18 ]
Kramer B. [21 ,36 ]
Kramer W. [21 ]
机构
[1] U. de Biochimie Physiologique, Univ. Catholique de Louvain, B-1348 Louvain-la-Neuve
[2] Dipto. Genet. Biol. Microrganismi, Università di Milano, I-20133 Milano
[3] Martinsrieder Inst. F. Protein S., Max-Planck-Inst. für Biochemie, D-82152 Martinsried
[4] Institut für Biologie IV, Mikrobiologie, RWTH-Aachen, D-52056, Worringerweg
[5] Depto. de Microbiología II, Faculdad de Farmacia, Universidad Complutense
[6] Laboratorio de Genetica Molecular, Instituto Gulbenkian de Ciencia, E-2781 Oeiras Codex
[7] Microbiology Group, Intl. Ctr. Genetic Eng. and Biotech., I-34012 Trieste
[8] Biotech. Ctr. Anim. and Plant Hlth., Queens University of Belfast, Belfast BT9 5PX, Newforge Lane
[9] Genotype GmbH, D-69259 Wilhelmsfeld
[10] Dipartimento di Chimica Biologica, Università di Padova, I-35121 Padova
[11] Dipartimento di Biologia, Univ. di Roma 'Tor Vergata', I-00133 Roma, via della Ricerca Scientifica
[12] Depto. de Biol. Celular y Molecular, Facultad de Ciencias, Universidad de La Coruna, La Coruna
[13] Ctr. de Genet. Moléculaire, CNRS, Univ. Pierre et Marie Curie
[14] Katholieke Universiteit Leuven, Laboratory of Gene Technology, B-3001 Leuven
[15] Deutsches Krebsforschungszentrum, Department for Applied Virology
[16] U. de Genet. Molec. des Levures, Department of Biotechnologies, Institut Pasteur, F-75724 Paris Cedex 15
[17] Unité de Microbiologie, Fac. Univ. Sci. Agronom. de Gembloux, B-5030 Gembloux
[18] Inst. für Mikrobiologie, Johann Wolfgang Goethe-Univ. F., D-60439 Frankfurt
[19] Inst. Invest. Biomed. del C.S.I.C., Departamento de Bioquímica, Facultad de Medicina de la U.A.M
[20] Dipto. Biol. Cell. e dello Sviluppo, Univ. di Roma La Sapienza, I-00185 Roma
[21] Institut für Molekulare Genetik, Georg-August-Universität, D-37077 Göttingen
[22] Lab. Microbiologie Genet. URA 1481, Université Louis Pasteur/CNRS, Institut de Botanique, F-67083 Strasbourg Cedex
[23] Microsynth GmbH, CH-9436 Balgach
[24] Dept. Biochem. Appl. Molec. Biol., UMIST, Manchester M60 1QD, Sackville Street
[25] Institut de Biochimie Cellulaire, CNRS, F-33077 Bordeaux Cedex
[26] Yeast Genetics, Institute of Molecular Medicine, John Radcliffe Hospital
[27] Dipto. Biochim. e Fisiol. Generali, Università di Milano, I-20133 Milano
[28] Institute of Microbiology, Wroclaw University, P-51148 Wroclaw
[29] Genome Sequencing Center, Department of Genetics, Washington Univ. School of Medicine, St Louis
[30] Dipto. di Agrobiologia e Agrochimica, Università della Tuscia, I-01100 Viterbo, via S. Camillo de Lellis
[31] AGON GmbH, D-12489 Berlin
[32] Inst. for Molecular Plant Sciences, Leiden University, NL-2333 AL Leiden
[33] Dept. of Microbiology and Enzymology, Delft University of Technology, NL-2628 BC Delft
[34] MWG-BIOTECH GmbH, D-85560 Ebersberg
[35] Centro de Biotecnología, Camagüey
[36] Abteilung Klinische Biochemie, Zentrum Innere Medizin, Georg-August-Universität, D-37075 Göttingen
关键词
D O I
10.1038/387s081
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学科分类号
摘要
The complete nucleotide sequence of Saccharomyces cerevisiae chromosome VII has 572 predicted open reading frames (ORFs), of which 341 are new. No correlation was found between G+C content and gene density along the chromosome, and their variations are random. Of the ORFs, 17% show high similarity to human proteins. Almost half of the ORFs could be classified in functional categories, and there is a slight increase in the number of transcription (7.0 %) and translation (5.2 %) factors when compared with the complete S. cerevisiae genome. Accurate verification procedures demonstrate that there are less than two errors per 10,000 base pairs in the published sequence.
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页码:81 / 84
页数:3
相关论文
共 30 条
  • [1] Oliver S.G., Et al., Nature, 357, pp. 38-46, (1992)
  • [2] Capieaux E., Ulaszewski S., Balzi E., Goffeau A., Yeast, 7, pp. 275-280, (1991)
  • [3] Chen W., Et al., Yeast, 7, pp. 287-299, (1991)
  • [4] Dujon B., Et al., Nature, 369, pp. 371-378, (1994)
  • [5] Dujon B., Trends Genet., 12, pp. 263-270, (1996)
  • [6] Klein P., Kanehisa M., Delisi C., Biochim. Biophys. Acta, 815, pp. 468-476, (1985)
  • [7] Goffeau A., Slonimski P., Nakai K., Risler J.L., Yeast, 9, pp. 691-702, (1993)
  • [8] Nakai K., Kanehisa M., Genomics, 14, pp. 897-911, (1992)
  • [9] Woolford J.L., Warner J.R., The Molecular and Cellular Biology of the Yeast Saccharomyces, 1, pp. 597-598, (1991)
  • [10] Milosavljevic A., Jurka J., Comput. Adv. Biosci., 9, pp. 409-411, (1993)