Sphincter of Oddi dysfunction

被引:16
作者
Menees S. [1 ]
Elta G.H. [1 ]
机构
[1] Division of Gastroenterology, University of Michigan, 3912 Taubman Center, Ann Arbor, MI 48109
关键词
Endoscopic Sphincterotomy; Hepatobiliary Scintigraphy; Biliary Dyskinesia; Oddi Dysfunction; Biliary Sphincterotomy;
D O I
10.1007/s11938-005-0003-2
中图分类号
学科分类号
摘要
Sphincter of Oddi dysfunction (SOD) is a benign noncalculous obstruction of bile or pancreatic drainage at the level of the sphincter of Oddi. The disorder is clinically associated with either biliary pain or idiopathic pancreatitis, depending on the portion of the sphincter affected. Patients with suspected SOD are subdivided into three categories: these are type I, II, and III, depending on associated clinical evidence for the diagnosis. Multiple noninvasive tests have been utilized to aid in the diagnosis but have been complicated by poor sensitivity and specificity. Sphincter of Oddi manometry is the gold standard for confirming the diagnosis, although questions remain about its sensitivity and specificity. Sphincterotomy of the affected portion of the sphincter is the treatment of choice and has been shown effective for palliation of symptoms in two sham-controlled studies of patients with suspected type II biliary SOD. Copyright © 2005 by Current Science Inc.
引用
收藏
页码:109 / 115
页数:6
相关论文
共 47 条
[1]
Coelho J.C., Wiederkehr J.C., Motility of Oddi's sphincter: Recent developments and clinical applications, Am. J. Surg., 172, pp. 48-51, (1996)
[2]
Becker J.M., Physiology of motor function of the sphincter of Oddi, Surg. Clin. North Am., 73, pp. 1291-1309, (1993)
[3]
Guelrud M., Mendoza S., Mujica V., Et al., Sphincter of Oddi (SO) motor function in patients with symptomatic gallstones, Gastroenterology, 104, (1993)
[4]
Guelrud M., Mendoza S., Rossiter G., Et al., Sphincter of Oddi manometry in healthy volunteers, Dig. Dis. Sci., 35, (1990)
[5]
Ruffolo T.A., Sherman S., Lehman G.A., Et al., Gallbladder ejection fraction and its relationship to sphincter of Oddi dysfunction, Dig. Dis. Sci., 39, (1994)
[6]
Black N.A., Thompson E., Sanderson C.F.B., Symptoms and health status before and six weeks after open cholecystectomy: A European cohort study, Gut, 35, pp. 1301-1305, (1994)
[7]
Luman W., Adams W.H., Nixon S.N., Et al., Incidence of persistent symptoms after laparoscopic cholecystectomy: A prospective study, Gut, 39, (1996)
[8]
Bar-Meir S., Halpern Z., Bardan E., Et al., Frequency of papillary dysfunction among cholecystectomized patients, Hepatology, 4, pp. 328-330, (1984)
[9]
Neoptolemos J.P., Bailey I.S., Carr-Locke D.L., Sphincter of Oddi dysfunction: Results of treatment by endoscopic sphincterotomy, Br. J. Surg., 75, pp. 454-459, (1988)
[10]
Sherman S., Troiano F.P., Hawes R.H., Et al., Frequency of abnormal sphincter of Oddi manometry compared with the clinical suspicion of sphincter of Oddi dysfunction, Am. J. Gastroenterol., 86, (1991)