Therapy-resistant depression with fatigue. A case of presumed streptococcal-associated autoimmune disorder

被引：10

作者：

Bechter K. ^{[1
,2
]}

Bindl A. ^{[2
]}

Horn M. ^{[2
]}

Schreiner V. ^{[2
]}

机构：

[1] Abteilung Psychiatrie II, Bezirkskrankenhaus, Universität Ulm, Günzburg 89312

[2] Abteilung Psychiatrie II, Bezirkskrankenhaus, Universität Ulm, Günzburg

来源：

Der Nervenarzt | 2007年 / 78卷 / 3期

关键词：

Autoimmunity; Borrelia; Depression; Fatigue; Streptococci;

D O I：

10.1007/s00115-006-2178-8

中图分类号：

学科分类号：

摘要：

After a tick bite and erythema chronicum migrans, a 31-year-old patient developed headaches, fatigue, multilocular pain and therapy-resistant depression with cognitive disturbances. Antibodies against Borrelia and Borna disease virus, high antibody titers against streptococci at the point of most severe depression and blood-CSF barrier dysfunction were found. Streptococcal antibody titers were normal 2 years before and 4 years after. With penicillin treatment and tonsillectomy, therapy-resistant depression improved. We suggest that the whole syndrome was streptococcal-associated autoimmune disease. © 2006 Springer Medizin Verlag.

引用

页码：338 / 341

页数：3

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