One-dimensional mean computed tomography value evaluation of ground-glass opacity on high-resolution images

被引：79

作者：

Kitami A. ^{[1
,2
]}

Kamio Y. ^{[1
,2
]}

Hayashi S. ^{[1
,2
]}

Suzuki K. ^{[1
,2
]}

Uematsu S. ^{[1
,2
]}

Gen R. ^{[1
,2
]}

Suzuki T. ^{[1
,2
]}

Kadokura M. ^{[1
,2
]}

机构：

[1] Respiratory Disease Center, Showa University Northern Yokohama Hospital, 35-1 Chigasaki-Chuo, Tsuzuki-ku

[2] Division of Chest Surgery, Showa University School of Medicine, Tokyo

来源：

General Thoracic and Cardiovascular Surgery | 2012年 / 60卷 / 7期

关键词：

Bronchioloalveolar carcinoma; Follow-up; Ground-glass opacity; Lung cancer; Mean computed tomography value;

D O I：

10.1007/s11748-012-0066-7

中图分类号：

学科分类号：

摘要：

Objective: Differentiation of atypical adenomatous hyperplasia (AAH), bronchioloalveolar carcinoma (BAC), and invasive carcinoma on computed tomography (CT) is useful for determining "follow-up or resection" strategies for lesions displaying ground-glass opacity (GGO). The purpose of this study is to evaluate one-dimensional quantitative CT values of GGO on high-resolution CT (HRCT) images using computer-aided diagnosis. Methods: Between April 2001 and March 2010, a total of 44 nodules in 42 patients with pure or mixed GGOs ≤2 cm were retrospectively evaluated. Maximum diameter and one-dimensional mean CT (m-CT) value of the diameter were measured using a computer graphics support system (HOPE/DrABLE-EX, Fujitsu, Tokyo, Japan) that displays a CT density profile across the tumor. Results: m-CT values were -682 ± 64 HU (range) for AAH lesions, -544 ± 179 (range) for Type A lesions, -496 ± 147 (range) for Type B lesions, and -371 ± 142 (range) for invasive lesions. AAH lesions had a significantly lower m-CT value than Type B lesions. AAH, Type A, and Type B lesions had significantly lower m-CT values than invasive lesions (p < 0.05). All seven GGO lesions with a maximum diameter B1 cm and m-CT value ≤-600 HU were pre-invasive lesions, while 16 of 22 (73%) cases with maximum diameter ≤1 cm and m-CT value >-600 HU were invasive lesions. Conclusion: Observation may be indicated for GGO lesions with a maximum diameter ≤1 cm and m-CT value ≤-600 HU. © The Author(s) 2012.

引用

页码：425 / 430

页数：5

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