Impaired clearance of apoptotic cells in systemic lupus erythematosus: challenge of T and B cell tolerance.

[1] Winkler TH(1991)IgG human monoclonal anti- DNA autoantibodies from patients with systemic lupus erythematosus Clin Exp Immunol 85 379-385

[2] Jahn S(1992)Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas Eur J Immunol 22 1719-1728

[3] Kalden JR(1997)Polyoma induced autoimmunity to DNA: experimental systems and clinical observations in human SLE Lupus 6 325-326

[4] Winkler TH(1995)In vivo expression of a single viral DNA-binding protein generates systemic lupus erythematosus-related autoimmunity to double-stranded DNA and histones Proc Natl Acad Sci U S A 92 12393-12397

[5] Fehr H(1995)Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus J Clin Invest 95 531-541

[6] Kalden JR(1997)Histone-specific Th0 and Th1 clones derived from systemic lupus erythematosus patients induce double-stranded DNA antibody production Arthritis Rheum 40 2162-2171

[7] Rekvig O(1994)Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes [see comments] J Exp Med 179 1317-1330

[8] Moens U(1995)Novel packages of viral and self-antigens are generated during apoptosis J Exp Med 181 1557-1561

[9] Seternes OM(1997)Proteins phosphorylated during stress-induced apoptosis are common targets for autoantibody production in patients with systemic lupus erythematosus J Exp Med 185 843-854

[10] Hey AW(1998)Distinct cleavage products of nuclear proteins in apoptosis and necrosis revealed by autoantibody probes Cell Death Differ 5 183-190

[1] Winkler TH(1991)IgG human monoclonal anti- DNA autoantibodies from patients with systemic lupus erythematosus Clin Exp Immunol 85 379-385

[2] Jahn S(1992)Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas Eur J Immunol 22 1719-1728

[3] Kalden JR(1997)Polyoma induced autoimmunity to DNA: experimental systems and clinical observations in human SLE Lupus 6 325-326

[4] Winkler TH(1995)In vivo expression of a single viral DNA-binding protein generates systemic lupus erythematosus-related autoimmunity to double-stranded DNA and histones Proc Natl Acad Sci U S A 92 12393-12397

[5] Fehr H(1995)Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus J Clin Invest 95 531-541

[6] Kalden JR(1997)Histone-specific Th0 and Th1 clones derived from systemic lupus erythematosus patients induce double-stranded DNA antibody production Arthritis Rheum 40 2162-2171

[7] Rekvig O(1994)Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes [see comments] J Exp Med 179 1317-1330

[8] Moens U(1995)Novel packages of viral and self-antigens are generated during apoptosis J Exp Med 181 1557-1561

[9] Seternes OM(1997)Proteins phosphorylated during stress-induced apoptosis are common targets for autoantibody production in patients with systemic lupus erythematosus J Exp Med 185 843-854

[10] Hey AW(1998)Distinct cleavage products of nuclear proteins in apoptosis and necrosis revealed by autoantibody probes Cell Death Differ 5 183-190