Treatment of recurrent hepatitis C following liver transplantation

被引:4
作者
Bizollon T. [1 ]
Ducerf C. [1 ]
Baulieux J. [1 ]
Trepo C. [1 ]
机构
[1] Hepatology Unit, Hotel-Dieu, Lyon Cedex 02
关键词
Cholestatic Hepatitis; Follow Liver Transplantation; Liver Transplant Recipient; Liver Transplantation; Orthotopic Liver Transplantation;
D O I
10.1007/s11894-999-0081-8
中图分类号
学科分类号
摘要
Cirrhosis due to hepatitis C virus infection is now the most common indication for liver transplantation in Western Europe and the United States. In the absence of effective prophylaxis, recurrent hepatitis C virus infection is almost inevitable. Although the natural history and intermediateterm outcome of recurrent infection with hepatitis C virus are now better documented, factors that may influence the recurrence of hepatitis and consequent progression of graft disease remain unclear. Interferon used as a single agent for the treatment of recurrent infection has proven unsatisfactory. Early intervention for recurrent infection with the combination of interferon and ribavirin appears promising, and this approach may prevent or delay progression of hepatitis C virus-related graft disease after liver transplantation. © 1999, Current Science Inc.
引用
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页码:15 / 19
页数:4
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