Retinopathy of prematurity in VLBW and extreme LBW babies

被引：26

作者：

P. M. C. Nair

A. Ganesh

S. Mitra

Shyam S. Ganguly

机构：

[1] Neonatal Division, Department of Child Health, Muscat

[2] Department of Ophthalmology, Sultan Qaboos University Hospital, Muscat

[3] Department of Epidemiology, Sultan Qaboos University Hospital, Muscat

[4] Neonatal and Pediatric ICU, Department of Child Health, Sultan Qaboos University Hospital, Muscat

来源：

The Indian Journal of Pediatrics | 2003年 / 70卷 / 4期

关键词：

Outcome; Retinopathy of prematurity; Risk factors; Very low birth weight and extreme low birth weight babies;

D O I：

10.1007/BF02723585

中图分类号：

学科分类号：

摘要：

Objective: This is a hospital-based, prospective clinical study to determine the incidence, risk factors, and outcome of extreme low birth weight and very low birth weight pre-term babies with retinopathy of prematurity (ROP) at the Sultan Qaboos University Hospital, Oman. Methods: All babies with a birth weight=/ <1500 g and gestational age =/< 32 weeks admitted in the Neonatal Unit, were screened for ROP between 4 to 6 weeks of age and staged according to the international classification and were followed up until complete vascularization of the retina. Fifty nine babies formed the study group. Results: The overall incidence of ROP was 25.4% (15 out of 59), of which 6 babies had severe ROP and underwent cryotherapy/laser. All babies with ROP had a birth weight <1250 g and were born before 31 weeks of gestation. Conclusion: ROP is a multifactorial disease, the immature retina of the pre-term baby being the primary factor. Incidence and severity was inversely proportional to birth weight and gestational age. Multiple logistic regression analysis showed that sepsis and total parenteral nutrition to be highly significant risk factors. Repeated blood transfusions, hypotension and congenital heart disease with left to right shunt were seen to be considerably associated with the development of ROP. A decrease in overall incidence and severity of ROP was observed in this study.

引用

页码：303 / 306

页数：3

共 17 条

[1]

Hussain N., Clive J., Bhandari V., Current incidence of retinopathy of prematurity, Pediatrics, 104, pp. 1-8, (1999)

[2]

Termote J., Schalij-Delfos N.E., Brouwers H.A.A., Donders A.R.T., Cats B.P., New developments in neonatology: Less severe retinopathy of prematurity?, J Pediatr Ophthalmol and Strabismus, 37, pp. 142-148, (2000)

[3]

Screening examination of premature infants for retinopathy of prematurity, Ophthalmology, 104, pp. 888-889, (1997)

[4]

Multicentric trial of cryotherapy: an international classification of retinopathy of prematurity, Arch Ophthalmol, 102, pp. 1130-1134, (1984)

[5]

Patil J., Deodhar J., Wagh S., Pandit A.N., High risk factors for development of retinopathy of prematurity, Indian Pediatr, 34, pp. 1024-1027, (1997)

[6]

Bassiouny M.R., Risk factors associated with retinopathy of prematurity, J Trop Pediatr, 42, pp. 355-358, (1996)

[7]

Maheshwari R., Kumar H., Paul V.K., Singh M., Deorari A.K., Tiwari H.K., Incidence and risk factors of retinopathy of prematurity in a tertiary care newborn unit in New Delhi, National Med J India, 9, pp. 211-214, (1996)

[8]

Bullard S.R., Donahue S.P., Feman S.S., Sinatra R.B., Walsh W.F., The decreasing incidence and severity of retinopathy of prematurity, J AAPOS, 3, pp. 46-52, (1999)

[9]

Lucey J.F., Dangman B., A re-examination of the role of oxygen in retrolental fibroplasia, Pediatrics, 73, pp. 82-96, (1984)

[10]

Inder T.E., Clement R.S., Austin N.C., Graham P., Darlow B.A., High iron status in very low birth weight infants is associated with an increased risk of retinopathy of prematurity, J Pediatr, 131, pp. 541-544, (1997)

← 1 2 →