Cerebrovascular diseases and depression

被引:31
作者
Himani Ghoge
Santvana Sharma
Shamash Sonawalla
Rajesh Parikh
机构
[1] Neuropsychiatry Clinic, Jaslok Hospital and Research Centre, Bombay 400 026
关键词
Mood Disorder; Trazodone; White Matter Hyperintensities; Hamilton Depression Rate Scale; Milnacipran;
D O I
10.1007/s11920-003-0048-7
中图分类号
学科分类号
摘要
Cerebrovascular diseases constitute a leading health hazard. The association between stroke and depression has been recognized for many years. Depression is the most common psychiatric disorder associated with cerebrovascular diseases, most episodes of post-stroke depression occur in the first 2 years after a cerebrovascular accident. Studies have found an association between lesion location, physical impairment, cognitive impairment, aphasia, and post-stroke depression. The location of the lesion in terms of proximity to the left frontal pole of the brain has a profound impact on the frequency and severity of post-stroke depression. Treatment modalities include pharmacotherapy, psychotherapy, electroconvulsive therapy, and rehabilitation. Understanding the psychologic and physical morbidity of post-stroke depression, as well as its timely, comprehensive treatment, are important for effective management. Copyright © 2003 by Current Science Inc.
引用
收藏
页码:231 / 238
页数:7
相关论文
共 57 条
[1]  
Robinson R.G., Kubos K.L., Starr L.B., Et al., Mood disorders in stroke patients: Importance of lesion location, Brain, 107, pp. 101-193, (1984)
[2]  
Parikh R.M., Robinson R.G., Mood and cognitive disorders following stroke, Neurology and Neurobiology, Animal Models of Dementia, pp. 103-135, (1987)
[3]  
Starkstein S.E., Robinson R.G., Honig M.A., Et al., Mood changes after right hemisphere lesions, Br. J. Psychiatry, 155, pp. 79-85, (1989)
[4]  
Parikh R.M., Robinson R.G., Lipsey J.R., Et al., The impact of post stroke depression on recovery in activities of daily living over a 2 year follow-up, Arch. Neurol., 47, pp. 785-789, (1990)
[5]  
Thomas A.J., O Brien J.T., Davis S., Et al., Ischaemic basis for deep white matter hyperintensities on major depression: A neuropathological study, Arch. Gen. Psychiatry, 59, pp. 785-792, (2002)
[6]  
Robinson R.G., Starkstein S.E., Neuropsychiatric aspects of cerebrovascular disorders, Textbook of Neuropsychiatry, pp. 242-253, (1997)
[7]  
Zillboorg G., A History of Medical Psychology, (1941)
[8]  
Meyer A., The anatomical facts and clinical varieties of traumatic insanity, Am. J. Insanity, 60, (1904)
[9]  
Bleuler E.P., Textbook of Psychiatry, (1951)
[10]  
Kraeplin E., Manic Depressive Insanity With Paranoia, (1921)