Lipids changes in liver cancer.

被引：64

作者：

Jiang J.T. ^{[1
]}

Xu N. ^{[1
]}

Zhang X.Y. ^{[1
]}

Wu C.P. ^{[1
]}

机构：

[1] Department of Tumor Biological Treatment, the Third Affiliated Hospital, Suzhou University, Changzhou

来源：

Journal of Zhejiang University SCIENCE B | 2007年 / 8卷 / 6期

基金：

中国国家自然科学基金;

关键词：

Lipids; Lipoprotein; Liver cancer; R735.7;

D O I：

10.1631/jzus.2007.B0398

中图分类号：

学科分类号：

摘要：

Liver is one of the most important organs in energy metabolism. Most plasma apolipoproteins and endogenous lipids and lipoproteins are synthesized in the liver. It depends on the integrity of liver cellular function, which ensures homeostasis of lipid and lipoprotein metabolism. When liver cancer occurs, these processes are impaired and the plasma lipid and lipoprotein patterns may be changed. Liver cancer is the fifth common malignant tumor worldwide, and is closely related to the infections of hepatitis B virus (HBV) and hepatitis C virus (HCV). HBV and HCV infections are quite common in China and other Southeast Asian countries. In addition, liver cancer is often followed by a procession of chronic hepatitis or cirrhosis, so that hepatic function is damaged obviously on these bases, which may significantly influence lipid and lipoprotein metabolism in vivo. In this review we summarize the clinical significance of lipid and lipoprotein metabolism under liver cancer.

引用

页码：398 / 409

页数：11

共 523 条

[1]

Albers J.J.(1977)Radioimmunoassay of human plasma Lp(a) lipoprotein J. Lipid. Res. 18 331-338

[2]

Adolphson J.L.(2002)Impaired capacity of acute-phase high density lipoprotein particles to deliver cholesteryl ester to the human HUH-7 hepatoma cell line Int. J. Biochem. Cell Biol. 34 370-381

[3]

Hazzard W.R.(1980)HDL cholesterol: biochemical aspects Klin. Wochenschr. 58 749-756

[4]

Artl A.(2002)Clinical significance of correlation between COX-2 and CD34-expression in dysplastic nodules Hepatology 36 445A-876

[5]

Marsche G.(1983)Hepatic lipase stimulates the uptake of high density lipoprotein cholesterol by hepatoma cells J. Lipid. Res. 24 869-60

[6]

Pussinen P.(1997)Lipoprotein(a) serum levels in patients with hepatocarcinoma Clin. Chim. Acta 262 53-186

[7]

Knipping G.(1985)Selective killing of human cancer cells by polyunsaturated fatty acids Prostaglandins Leukot. Med. 19 177-1062

[8]

Sattler W.(1986)Differential killing of human carcinoma cells supplemented with n-3 and n-6 polyunsaturated fatty acids J. Natl. Cancer Inst. 77 1053-228

[9]

Malle E.(1991)Lack of effect of acute alcohol ingestion on plasma lipids Clin. Chem. 37 1649-440

[10]

Assmann G.(1990)Alterations of lipid composition in Friend leukemia cell tumors in mice treated with tumor necrosis factor-alpha FEBS Lett. 260 225-16382

← 1 2 3 4 5 6 7 8 9 10 →