Cognitive impairment in patients with chronic pain: The significance of stress

被引：106

作者：

Robert P. Hart

James B. Wade

Michael F. Martelli

机构：

[1] Department of Psychiatry, VCU Health System, Richmond, VA 23298-0268

来源：

Current Pain and Headache Reports | 2003年 / 7卷 / 2期

关键词：

Chronic Pain; Pain Intensity; Cortisol Level; Fibromyalgia; Anterior Cingulate Cortex;

D O I：

10.1007/s11916-003-0021-5

中图分类号：

学科分类号：

摘要：

This review article examines the role of emotional distress and other aspects of suffering in the cognitive impairment that often is apparent in patients with chronic pain. Research suggests that pain-related negative emotions and stress potentially impact cognitive functioning independent of the effects of pain intensity. The anterior cingulate cortex is likely an integral component of the neural system that mediates the impact of pain-related distress on cognitive functions, such as the allocation of attentional resources. A maladaptive physiologic stress response is another plausible cause of cognitive impairment in patients with chronic pain, but a direct role for dysregulation of the hypothalamic-pituitary-adrenocortical axis has not been systematically investigated. Copyright © 2003 by Current Science Inc.

引用

页码：116 / 126

页数：10

共 104 条

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