Neurologic paraneoplastic syndromes

被引：8

作者：

Dropcho E.J. ^{[1
]}

机构：

[1] Department of Neurology, Indiana University Medical Center, Indianapolis

来源：

Current Oncology Reports | 2004年 / 6卷 / 1期

关键词：

Thymoma; Paraneoplastic Syndrome; Cerebellar Degeneration; Limbic Encephalitis; Neurologic Paraneoplastic Syndrome;

D O I：

10.1007/s11912-996-0006-8

中图分类号：

学科分类号：

摘要：

Paraneoplastic disorders can affect any part of the central or peripheral nervous system. Although relatively uncommon, these disorders are a significant cause of severe neurologic disability among cancer patients. Many paraneoplastic disorders are believed to be caused by an autoimmune response directed against shared neural tumor antigens. This article summarizes the clinical features, possible autoimmune pathophysiology, and management issues for patients with paraneoplastic disorders. Copyright © 2004 by Current Science Inc.

引用

页码：26 / 31

页数：5

共 48 条

[1]

Graus F., Keime-Guibert F., Rene R., Et al., Anti-Hu-associated paraneoplastic encephalomyelitis: Analysis of 200 patients, Brain, 124, pp. 1138-1148, (2001)

[2]

Sillevis Smitt P., Grefkens J., de Leeuw B., Et al., Survival and outcome in 73 anti-Hu positive patients with paraneoplastic encephalomyelitis/sensory neuronopathy, J. Neurol., 249, pp. 745-753, (2002)

[3]

Mason W.P., Graus F., Lang B., Et al., Small-cell lung cancer, paraneoplastic cerebellar degeneration and the Lambert-Eaton myasthenic syndrome, Brain, 120, pp. 1279-1300, (1997)

[4]

Rojas I., Graus F., Keime-Guibert F., Et al., Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies, Neurology, 55, pp. 713-715, (2000)

[5]

Alamowitch S., Graus F., Uchuya M., Et al., Limbic encephalitis and small cell lung cancer: Clinical and immunological features, Brain, 120, pp. 923-928, (1997)

[6]

Gultekin S.H., Rosenfeld M.R., Voltz R., Et al., Paraneoplastic limbic encephalitis: Neurological symptoms, immunological findings and tumour association in 50 patients, Brain, 123, pp. 1481-1494, (2000)

[7]

Bataller L., Graus F., Saiz A., Et al., Clinical outcome in adult onset idiopathic or paraneoplastic opsoclonus-myoclonus, Brain, 124, pp. 437-443, (2001)

[8]

Rudnick E., Khakoo Y., Antunes N.L., Et al., Opsoclonus-myoclonus-ataxia syndrome in neuroblastoma: Clinical outcome and antineuronal antibodies: A report from the Children's Cancer Group, Med. Pediatr. Oncol., 36, pp. 612-622, (2001)

[9]

Vernino S., Tuite P., Adler C.H., Et al., Paraneoplastic chorea associated with CRMP-5 neuronal antibody and lung carcinoma, Ann. Neurol., 51, pp. 625-630, (2002)

[10]

Rosenfeld M.R., Eichen J.G., Wade D.F., Et al., Molecular and clinical diversity in paraneoplastic immunity to Ma proteins, Ann. Neurol., 50, pp. 339-348, (2001)

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