Correlation of right ventricular dysfunction parameters and pulmonary vascular obstruction score in acute pulmonary embolism in a porcine model

被引：5

作者：

Groth M. ^{[1
]}

Henes F.O. ^{[1
]}

Müllerleile K. ^{[2
]}

Adam G. ^{[1
]}

Begemann P.G.C. ^{[1
]}

Regier M. ^{[1
]}

机构：

[1] Department of Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Hamburg 20246

[2] Department of Cardiology/Angiology, University Medical Center Hamburg-Eppendorf, Hamburg 20246

来源：

Emergency Radiology | 2010年 / 17卷 / 5期

关键词：

Acute pulmonary embolism; Animal model; Pulmonary-vascular obstruction; Right ventricular function;

D O I：

10.1007/s10140-010-0872-0

中图分类号：

学科分类号：

摘要：

This paper aims to non-invasively determine right ventricular dysfunction parameters (RVDP) in acute pulmonary embolism (APE) and to correlate these parameters with a computed tomography (CT)-based pulmonary artery obstruction score (OS). In seven domestic pigs, magnetic resonance imaging (MRI) was performed before (n=7) and after (n=5) APE was induced. Analysis of relative changes in right ventricular stroke volume (RVSV%), output (RVO%), end-systolic (RVESV%), end-diastolic volume (RVEDV%), and heart rate (HR%) was performed. Additionally, for the determination of the OS, all animals underwent contrast-enhanced CT-pulmonary angiography. The CT-based OS correlated strongly with RVSV% (r=0.9576; p=0.0104) and RVO% (r=0.9703; p=0.0061). Contrarily, almost no correlation could be demonstrated for the OS and the increase of RVESV % (r=0.3850; p=0.5222), RVEDV% (r=0.1830; p=0.7683), and HR% (r=0.5494; p=0.3375). The results of this experimental study underline that the CT-based OS correlates with RVDP as determined by cardiac MRI and might be a helpful tool for the severity assessment in APE. © 2010 Am Soc Emergency Radiol.

引用

页码：367 / 374

页数：7

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