SNAP-II predicts severe intraventricular hemorrhage and chronic lung disease in the neonatal intensive care unit

被引:35
作者
Chien L.-Y. [1 ,2 ]
Whyte R. [3 ]
Thiessen P. [1 ]
Walker R. [4 ]
Brabyn D. [5 ]
Lee S.K. [1 ,2 ]
机构
[1] Department of Pediatrics, University of British Columbia, Vancouver, BC
[2] Centre for Community Health and Health Evaluation Research, Vancouver, BC
[3] Department of Pediatrics, Dalhousie University, Halifax, NS
[4] Department of Pediatrics, University of Ottawa, Ottawa, ON
[5] Department of Pediatrics, Royal Columbian Hospital, New Westminster, BC
基金
英国医学研究理事会;
关键词
D O I
10.1038/sj.jp.7210585
中图分类号
学科分类号
摘要
Objective: To determine whether the Score for Neonatal Acute Physiology, Version II (SNAP-II), improved prediction of severe (≥grade III) intraventricular hemorrhage (IVH) and chronic lung disease (CLD) when compared to models using gestational age (GA) and traditional risk factors (e.g., Apgar score, small-for-gestational-age, sex, outborn status). Study Design: We examined 4226 infants ≤32 weeks' GA admitted to 17 Canadian neonatal intensive care units between 1996 and 1997. We compared prediction models for severe IVH and CLD, with and without SNAP-II. Results: SNAP-II was a significant and independent predictor of severe IVH and CLD. Addition of SNAP-II to models using GA and traditional risk variables significantly (p<0.05) improved model prediction (AUC 0.8 for severe IVH; 0.83 for CLD). Models were well calibrated (p>0.05 for Hosmer-Lemeshow goodness of fit test). Conclusion: Addition of SNAP-II to models using GA and traditional risk factors significantly improves prediction of severe IVH and CLD.
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页码:26 / 30
页数:4
相关论文
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