Maternal floor infarction of the placenta: Association with central nervous system injury and adverse neurodevelopmental outcome

被引:49
作者
Adams-Chapman I. [1 ]
Vaucher Y.E. [1 ]
Bejar R.F. [1 ]
Benirschke K. [1 ]
Baergen R.N. [1 ]
Moore T.R. [1 ]
机构
[1] Departments of Pediatrics/Division of Neonatology, Pathology and Reproductive Medicine, University of California at San Diego, San Diego, CA
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D O I
10.1038/sj.jp.7210685
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学科分类号
摘要
Objective: To compare cranial ultrasound studies and neurodevelopmental outcome of preterm infants affected by maternal floor infarction (MFI) of the placenta to gestational age-matched controls over an 8-year period from a single institution. Study Design: Retrospective case/control study. Results: Compared to gestational age-matched controls, infants born to mothers with MFI had a higher incidence of CNS injury on neonatal cranial ultrasound examinations and at follow-up were more likely to have a suspicious or abnormal neurologic examination. MFI cases had lower developmental scores in all areas tested and were more likely to have neurodevelopmental impairment. Conclusion: Infants born to mothers with MFI should have serial neonatal cranial ultrasound examinations to detect CNS injury and neurodevelopmental assessment during early childhood.
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页码:236 / 241
页数:5
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