Pathogenesis of cartilage calcification: mechanisms of crystal deposition in cartilage.

被引：12

作者：

Boskey A.L. ^{[1
]}

机构：

[1] Hospital for Special Surgery, 535 East 70th Street, New York, 10021, NY

来源：

Current Rheumatology Reports | 2002年 / 4卷 / 3期

关键词：

Growth Plate; Calcium Oxalate; Hyaline Cartilage; Crystal Deposition; Matrix Vesicle;

D O I：

10.1007/s11926-002-0072-3

中图分类号：

学科分类号：

摘要：

Apatite crystals form in physiologically calcified tissues, including the hyaline cartilage of the epiphyseal growth plate. While apatite crystals appear as unwanted deposits in other cartilage sites, more frequently, crystalline materials other than or in addition to apatite develop in dystrophic cartilage deposits. These crystalline materials include calcium pyrophosphate dihydrate and other calcium phosphate and calcium carbonate phases, monosodium urate, calcium oxalate, cholesterol, and crystallized proteins. This review describes the physical chemistry of crystal deposition and the events that occur in the growth plate as a basis for understanding the pathogenesis of nonphysiologic crystal deposition in cartilage.

引用

页码：245 / 251

页数：6

共 148 条

[1]

Hunziker EB(1994)Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes Microsc Res Tech 28 505-519

[2]

Szuwart T(1998)Ultrastructural aspects of cartilage formation, mineralization, and degeneration during primary antler growth in fallow deer (Dama dama) Anat Anz 180 501-510

[3]

Kierdorf H(1997)Postnatal development of the cruciate ligament insertions in the rat knee: morphological evaluation and immunohistochemical study of collagens types I and II Acta Anat (Basel) 160 261-268

[4]

Kierdorf U(1994)Crystals and arthritis Dis Mon 40 255-299

[5]

Clemen G(1995)Articular chondrocalcinosis of the humeral head in greyhounds Am J Vet Res 56 473-480

[6]

Messner K(1999)New developments in the pathogenesis of articular cartilage calcification Curr Rheumatol Rep 1 121-127

[7]

McCarty DJ(1991)Spondyloarthropathy in progressive ankylosis mice: ultrastructural features of the intervertebral disk Acta Anat (Basel) 141 36-41

[8]

Woodard JC(1990)The distribution of calcific deposits in intervertebral discs of the lumbosacral spine Clin Orthop 254 303-310

[9]

Riser WH(1996)Calcium pyrophosphate dihydrate crystal deposition disease: frequency of tendon calcification about the knee J Rheumatol 23 883-888

[10]

Morrone AA(1992)Calcification of the auricular cartilage: a case report and literature review Cutis 50 55-57

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