Electrospun scaffolds for bone tissue engineering

被引:52
作者
Di Martino A. [1 ]
Liverani L. [2 ]
Rainer A. [2 ]
Salvatore G. [1 ]
Trombetta M. [2 ]
Denaro V. [1 ]
机构
[1] Department of Orthopaedics and Trauma Surgery, University Campus Bio-Medico of Rome, 00128 Rome, Via A ́ lvaro del Portillo
[2] CIR - Tissue Engineering Laboratory, University Campus Bio-Medico of Rome, 00128 Rome, Via A ́ lvaro del Portillo
关键词
Bone tissue engineering; Electrospinning; Nanofibers; Scaffold; Stem cells;
D O I
10.1007/s12306-011-0097-8
中图分类号
学科分类号
摘要
Tissue engineering aims to regenerate native tissues and will represent the alternative choice of standard surgery for different kind of tissue damages. The fundamental basis of tissue engineering is the appropriate selection of scaffolds and their morphological, mechanical, chemical, and biomimetic properties, closely related to cell lines that will be seeded therein. The aim of this review is to summarize and report the innovative scientific contributions published in the field of orthopedic tissue engineering, in particular about bone tissue engineering. We have focused our attention on the electrospinning technique, as a scaffold fabrication method. Electrospun materials are being evaluated as scaffolds for bone tissue engineering, and the results of all these studies clearly indicate that they represent suitable potential substrates for cell-based technologies. © 2011 Springer-Verlag.
引用
收藏
页码:69 / 80
页数:11
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