Treatment of hypertension and prevention of ischemic stroke

被引:32
作者
Aronow W.S. [1 ]
Frishman W.H. [1 ]
机构
[1] Department of Medicine, New York Medical College, Valhalla, NY 10595, Munger Pavilion
关键词
Losartan; Antihypertensive Drug; Antihypertensive Drug Therapy; Perindopril; Systolic Hypertension;
D O I
10.1007/s11886-004-0010-2
中图分类号
学科分类号
摘要
Data clearly indicate that treatment with antihypertensive drugs reduces the incidence of all strokes in men (by 34%), women (by 38%), elderly persons (by 36%), including those older than 80 years (by 34%), younger persons, those with systolic and diastolic hypertension, persons with isolated systolic hypertension, and in those with a history of stroke or transient ischemic attack (by 28%). Blood pressure should be reduced to less than 140/90 mm Hg. The overall data also suggest that reduction of stroke in persons with hypertension is related more to a reduction in blood pressure than to the type of antihypertensive drugs used. Copyright © 2004 by Current Science Inc.
引用
收藏
页码:124 / 129
页数:5
相关论文
共 32 条
[1]  
Garland C., Barrett-Connor E., Suarez L., Criqui M.H., Isolated systolic hypertension and mortality after age 60 years, Am. J. Epidemiol., 118, pp. 365-376, (1983)
[2]  
Stokes III J., Kannel W.B., Wolf P.A., Et al., The relative importance of selected risk factors for various manifestations of cardiovascular disease among men and women from 35 to 64 years old: 30 years of follow-up in the Framingham Study, Circulation, 75, SUPPL. V, (1987)
[3]  
Wolf P.A., Cerebrovascular disease in the elderly, Cardiovascular Disease in the Elderly Patient, pp. 125-147, (1994)
[4]  
Aronow W.S., Ahn C., Gutstein H., Risk factors for new atherothrombotic brain infarction in 664 older men and 1,488 older women, Am. J. Cardiol., 77, pp. 1381-1383, (1996)
[5]  
The sixth report of the Joint National Committee on the detection, evaluation, and treatment of high blood pressure (JNC VI), Arch. Intern. Med., 157, pp. 2413-2444, (1997)
[6]  
The Australian Therapeutic Trial in Mild Hypertension, Lancet, 1, pp. 1261-1267, (1980)
[7]  
MRC trial of mild hypertension: Principal results, Br. Med. J., 291, pp. 97-104, (1985)
[8]  
MRC trial of treatment of hypertension in older adults: Principal results, Br. Med. J., 304, pp. 405-412, (1992)
[9]  
Amery A., Birkenhager W., Brixko P., Et al., Morbidity and mortality results from the European Working Party on High Blood Pressure in the Elderly trial, Lancet, 1, pp. 1349-1354, (1985)
[10]  
Coupe J., Warrender T.S., Randomised trial of the treatment of hypertension in elderly patients in primary care, Br. Med. J., 293, pp. 1145-1151, (1986)