Fibrin sealing versus stapling of hernia meshes in an onlay model in the rat

被引:54
作者
Petter-Puchner A.H. [1 ]
Fortelny R. [2 ]
Mittermayr R. [1 ]
Öhlinger W. [3 ]
Redl H. [1 ]
机构
[1] Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, 1200 Vienna
[2] II. Department of Surgery, Wilhelminenspital der Stadt Wien, Vienna
[3] Department of Pathology, City Hospital Krems, Lower Austria
关键词
Abdominal wall hernia; Biomechanics; Fibrin sealant; Histology; Onlay repair; Rat model;
D O I
10.1007/s10029-005-0009-7
中图分类号
学科分类号
摘要
Incisional and inguinal hernia repair are among the most common procedures of general surgery. Mesh fixation by means of staples or sutures may lead to severe complications. The use of fibrin sealant (FS) has been suggested as alternative, but data on biocompatibility and adhesive strength of FS in combination with macroporous meshes is limited. Ventral hernia (n=8 per group) was treated in rats in onlay technique with two types of meshes, fibrin sealed or stapled. TI-Mesh (TMxl) extralight and VYPROII (VPII) were tested 17 days post op. No failure in mechanical tests (tensile and burst strength) occurred in sealed or stapled meshes. Histology revealed equally good tissue integration and neovascularization in all groups. Fibrin sealant yields excellent fixation in experimental hernia repair. This rat model is suitable for testing meshes and fixation techniques. © Springer-Verlag 2005.
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页码:322 / 329
页数:7
相关论文
共 24 条
[1]  
McGreevy J.M., Goodney P.P., Birkmeyer C.M., Finlayson S.R., Laycock W.S., Birkmeyer J.D., A prospective study comparing the complication rates between laparoscopic and open ventral hernia repairs, Surg Endosc, 17, pp. 1778-1780, (2003)
[2]  
Neumayer L., Giobbie-Hurder A., Jonasson O., Fitzgibbons Jr. R., Dunlop D., Gibbs J., Reda D., Henderson W., Open mesh versus laparoscopic mesh repair of inguinal hernia, N Engl J Med, 350, pp. 1819-1827, (2004)
[3]  
Smith A.I., Royston C.M., Sedman P.C., Stapled and nonstapled laparoscopic transabdominal preperitoneal (TAPP) inguinal hernia repair. A prospective randomized trial, Surg Endosc, 13, pp. 804-806, (1999)
[4]  
Douglas J.M., Young W.N., Jones D.B., Lichtenstein inguinal herniorrhaphy using sutures versus tacks, Hernia, 6, pp. 99-101, (2002)
[5]  
Junge K., Klinge U., Klosterhalfen B., Mertens P.R., Rosch R., Schachtrupp A., Ulmer F., Schumpelick V., Influence of mesh materials on collagen deposition in a rat model, J Invest Surg, 15, pp. 319-328, (2002)
[6]  
Ladurner R., Mussack T., Small bowel perforation due to protruding spiral tackers: A rare complication in laparoscopic incisional hernia repair, Surg Endosc, 18, (2004)
[7]  
Paajanen H., Do absorbable mesh sutures cause less chronic pain than nonabsorbable sutures after Lichtenstein inguinal herniorraphy?, Hernia, 6, pp. 26-28, (2002)
[8]  
Katkhouda N., Mavor E., Friedlander M.H., Mason R.J., Kiyabu M., Grant S.W., Achanta K., Kirkman E.L., Narayanan K., Essani R., Use of fibrin sealant for prosthetic mesh fixation in laparoscopic extraperitoneal inguinal hernia repair, Ann Surg, 233, pp. 18-25, (2001)
[9]  
Pans A., Pierard G.E., A comparison of intraperitoneal prostheses for the repair of abdominal muscular wall defects in rats, Eur Surg Res, 24, pp. 54-60, (1992)
[10]  
Scheidbach H., Tamme C., Tannapfel A., Lippert H., Kockerling F., In vivo studies comparing the biocompatibility of various polypropylene meshes and their handling properties during endoscopic total extraperitoneal (TEP) patchplasty: An experimental study in pigs, Surg Endosc, 18, pp. 211-220, (2004)