Clinical diagnosis of cerebral amyloid angiopathy: Validation of the boston criteria

被引：58

作者：

Eric E. Smith

Steven M. Greenberg

机构：

[1] Neurology Clinical Trials Unit, Massachusetts General Hospital, Boston, MA 02114

来源：

Current Atherosclerosis Reports | 2003年 / 5卷 / 4期

关键词：

Intracerebral Hemorrhage; Cerebral Amyloid Angiopathy; Amyloid Precursor Protein Gene; Lobar Hemorrhage; Cortical Biopsy;

D O I：

10.1007/s11883-003-0048-4

中图分类号：

学科分类号：

摘要：

Cerebral amyloid angiopathy is a disorder in which deposition of amyloid within the arterial media and adventitia leads to intracerebral hemorrhage. Diagnosis during life has been hampered by the requirement for post-mortem examination for definitive diagnosis. The Boston Criteria for the diagnosis of cerebral amyloid angiopathy-related hemorrhage were developed in 1995 and 1996 in order to meet the need for a standardized set of diagnostic criteria that can be applied to living patients. Using a combination of clinical, radiologic, and pathologic data, these criteria reliably differentiate lobar intracerebral hemorrhage into categories of possible, probable, or definite based on the likelihood of underlying cerebral amyloid angiopathy. These criteria will be crucial for disease classification for future clinical studies. Copyright © 2003 by Current Science Inc.

引用

页码：260 / 266

页数：6

共 47 条

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