Exercise: an important component of treatment in the idiopathic inflammatory myopathies.

被引：10

作者：

Alexanderson H. ^{[1
]}

机构：

[1] Department of Physical Therapy, Rheumatology Unit D2:07, Karolinska University Hospital, Stockholm

来源：

Current Rheumatology Reports | 2005年 / 7卷 / 2期

关键词：

Myopathy; Resistive Exercise; Rheumatol; Muscle Biopsy; Myositis;

D O I：

10.1007/s11926-005-0063-2

中图分类号：

学科分类号：

摘要：

Resistive exercise is controversial for patients with idiopathic inflammatory myopathies. This paper provides an update on exercise and clinical assessment in these patients. The few published studies on this topic report unchanged disease activity from a variety of exercise regimens in patients in all stages of disease. Reduced disability was achieved in patients with polymyositis and dermatomyositis. In one study a slightly reduced impairment was reported in patients with inclusion body myositis, while in another study no objective reduction of disability could be detected. An increasing number of valid and reliable outcome measures are available for patients with polymyositis and dermatomyositis, but for patients with inclusion body myositis reliable and sensitive outcome measures are still needed.

引用

页码：115 / 124

页数：9

共 138 条

[1]

Mastaglia FL(2003)Inflammatory myopathies: clinical, diagnostic and therapeutic aspects Muscle Nerve 27 407-425

[2]

Garlepp MJ(2000)Aerobic capacity in adult dermatomyositis/polymyositis patients and healthy controls Arch Phys Med Rehabil 81 1-5

[3]

Phillips BA(1990)Incidence of polymyositis-dermatomyositis: a 20-year study of hospital diagnosed cases in Allegheny County, PA 1963–1982 J Rheumatol 17 1329-1334

[4]

Wiesinger GF(2002)Idiopathic inflammatory myopathies: epidemiology, classification, and diagnostic criteria Rheum Dis Clin North Am 28 723-741

[5]

Quittan M(2001)Polymyositis and dermatomyositis: short term and longterm outcome, and predictive factors of prognosis J Rheumatol 28 2230-2237

[6]

Nuhr M(2000)Increased expression of interleukin 1 alpha and MHC class 1 in muscle tissue of patients with chronic, inactive polymyositis and dermatomyositis J Rheumatol 27 940-948

[7]

Oddis CV(2002)Interleukin-1 alpha expression in capillaries and major histocompatability complex class I expression in type II muscle fibers from polymyositis and dermatomyositis: important pathogenic features independent of inflammatory cell clusters in muscle tissue Arthritis Rheum 46 1044-1055

[8]

Conte CG(2002)Reduced oxidative phosphorylation and proton efflux suggest reduced capillary blood supply in skeletal muscle of patients with dermatomyositis and polymyositis: a quantitative 31P-magnetic resonance spectroscopy and MRI study Brain 125 1635-1645

[9]

Steen VD(1995)Use of magnetic resonance imaging and P-31 magnetic resonance spectroscopy to detects and quantify muscle dysfunction in the amyopathic and myopathic variants of dermatomyositis Arthritis Rheum 38 68-77

[10]

Mastaglia FL(2003)Unfolding story of inclusion-body myositis and myopathies: role of misfolded proteins, amyloid-beta, cholesterol and aging J Child Neurol 18 185-190

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