Vitamin D status in mothers and their newborns in Iran

被引：113

作者：

Maghbooli Z. ^{[1
]}

Hossein-Nezhad A. ^{[1
]}

Shafaei A.R. ^{[1
]}

Karimi F. ^{[1
]}

Madani F.S. ^{[1
]}

Larijani B. ^{[1
]}

机构：

[1] Endocrinology and Metabolism Research Center, Tehran University of Medical Sciences, Shariati Hospital, Tehran 14114, North Kargar Avenue

来源：

BMC Pregnancy and Childbirth | / 7卷 / 1期

关键词：

Cord Blood; Head Circumference; Serum Vitamin; Cord Blood Sample; Maternal Weight Gain;

D O I：

10.1186/1471-2393-7-1

中图分类号：

学科分类号：

摘要：

Background: Adequate vitamin D concentrations during pregnancy are necessary to neonatal calcium homeostasis, bone maturation and mineralization. The aim of study is to evaluate serum vitamin D concentrations in mothers and their newborns and effect of vitamin D deficiency on pregnancy outcomes. Methods: 552 pregnant women were recruited from Tehran University educating hospitals in the winter of 2002. Maternal and cord blood samples were taken at delivery. The serum was assayed for 25-hydroxyvitamin D3, calcium, phosphorus and parathyroid hormone. Results: The prevalence of vitamin D deficiency in maternal and cord blood samples were 66.8% and 93.3%, respectively (<35 nmol/l). There was significant correlation between maternal and cord blood serum concentrations of vitamin D. In mothers with vitamin D deficiency, cord blood vitamin D concentrations was lower than those from normal mothers (P = .001). Also, a significant direct correlation was seen between maternal vitamin D intake and weight gain during pregnancy. Conclusion: Consideration to adequate calcium and vitamin D intake during pregnancy is essential. Furthermore, we think it is necessary to reconsider the recommendation for vitamin D supplementation for women during pregnancy. © 2007 Maghbooli et al; licensee BioMed Central Ltd.

引用

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