Pathogenesis of hyperuricemia: recent advances.

被引：28

作者：

Ghei M. ^{[1
]}

Mihailescu M. ^{[1
]}

Levinson D. ^{[1
]}

机构：

[1] Michael Reese Hospital, Department of Internal Medicine, 2929 South Ellis Avenue, Chicago, 60616, IL

来源：

Current Rheumatology Reports | 2002年 / 4卷 / 3期

关键词：

Uric Acid; Gout; Serum Uric Acid; Hyperuricemia; Uric Acid Level;

D O I：

10.1007/s11926-002-0076-z

中图分类号：

学科分类号：

摘要：

The literature on the pathogenesis of hyperuricemia have been limited to the discussion of metabolic syndromes associated with risk factors for atherosclerosis and hyperuricemia and the genetics of the juvenile form of hyperuricemic nephropathies. A few new mutations in the hypoxanthine-guanine phosphoribosyltransferase gene, which result in Lesch-Nyhan syndrome, have been described. In addition, some new insight has been gained in the renal handling of uric acid by the human kidney.

引用

页码：270 / 274

页数：4

共 67 条

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