Nutritional therapy in inflammatory bowel disease

被引:18
作者
O'Sullivan M. [1 ]
O'Morain C. [1 ]
机构
[1] Department of Clinical Medicine, Trinity College, Adelaide and Mental Hospital
关键词
Inflammatory Bowel Disease; Enteral Nutrition; Total Parenteral Nutrition; Inflammatory Bowel Disease Patient; Short Chain Fatty Acid;
D O I
10.1007/s11938-004-0040-2
中图分类号
学科分类号
摘要
Nutritional intervention is an important adjunctive therapy for patients with inflammatory bowel disease (IBD). The correction and maintenance of nutritional status, achieved by careful nutritional monitoring and intervention, should be an integral part of the multidisciplinary management of IBD throughout all stages of the disease. In acute Crohn's disease, enteral nutrition (polymeric and elemental) is an effective and safe primary therapy for many patients. Enteral diets should be considered as primary therapy in pediatric Crohn's disease patients, especially in children with poor nutritional status or growth impairment and in patients with severe drug-induced side effects. Total parenteral nutrition does not have a primary therapeutic role in IBD. Copyright © 2004 by Current Science Inc.
引用
收藏
页码:191 / 198
页数:7
相关论文
共 38 条
[1]  
O'Morain C., Segal A.W., Levi A.J., Elemental diet as primary treatment of acute Crohn's disease: A controlled trial, BMJ, 288, pp. 1859-1862, (1984)
[2]  
Fernandez-Banares F., Cabre E., Esteve-Comas M., Gassull M.A., How effective is enteral nutrition in inducing clinical remission in active Crohn's disease? A meta-analysis of the randomized clinical trials, J. Parenter. Enteral. Nutr., 19, pp. 356-364, (1995)
[3]  
Messori A., Trallori G., D'Albasio G., Et al., Defined-formula diets versus steroids in the treatment of active Crohn's disease: A meta-analysis, Scand. J. Gastroenterol., 31, pp. 267-272, (1996)
[4]  
Teahon K., Bjarnason I., Pearson M., Levi A.J., Ten years' experience with an elemental diet in the management of Crohn's disease, Gut, 31, pp. 1133-1137, (1990)
[5]  
Fell J.M., Paintin M., Arnaud-Battandier F., Et al., Mucosal healing and a fall in mucosal pro-inflammatory cytokine mRNA induced by a specific oral polymeric diet in paediatric Crohn's disease, Aliment. Pharm. Ther., 14, pp. 281-289, (2000)
[6]  
O'Sullivan M., O'Morain C., Nutritional therapy in Crohn's disease, Inflamm. Bowel Dis., 4, pp. 45-53, (1998)
[7]  
Akobeng A.K., Miller V., Stanton J., Et al., Double-blind randomized controlled trial of glutamine-enriched polymeric diet in the treatment of active Crohn's disease, J. Pediatr. Gastroenterol. Nutr., 30, pp. 78-84, (2000)
[8]  
Gassull M.A., Fernandez-Banares F., Cabre E., Et al., Fat composition may be a clue to explain the primary therapeutic effect of enteral nutrition in Crohn's disease: Results of a double blind randomised multicentre European trial, Gut, 51, pp. 164-168, (2002)
[9]  
Shanahan F., Probiotics and inflammatory bowel disease: From fads and fantasy to facts and future, Br. J. Nutr., 88, SUPPL. 1, (2002)
[10]  
Auvin S., Incidence, clinical presentation and localisation of pediatric inflammatory bowel disease at diagnosis in northern France (1998-99), Gut, 35, SUPPL. II, (2003)