Clinico-bacteriological study of neonatal septicemia in Hubli

被引:57
作者
Tallur S.S. [1 ,5 ]
Kasturi A.V. [2 ]
Nadgir S.D. [3 ]
Krishna B.V.S. [4 ]
机构
[1] Department of Microbiology, Hubli, Karnataka
[2] Department of Pediatrics, Hubli, Karnataka
[3] Karnatak Inst. of Medical Sciences, Hubli, Karnataka
[4] St. John's Medical College, Bangalore
[5] Department of Microbiology, Karnatak Inst. of Medical Sciences, Hubli 580 022, Karnataka
关键词
Bacteriological features; Clinical; Neonatal septicemia;
D O I
10.1007/BF02723654
中图分类号
学科分类号
摘要
Septicemia is a leading cause of neonatal morbidity and mortality in India. In a study of 242 infants with septicemia conducted between March 1996 & June 1997 at Hubli, Karnataka, 43.39% infants had 'very early onset' sepsis (VOS), 40.08%, had 'early onset' sepsis (EOS), and 16.53% 'late onset' sepsis (LOS). 54.55% neonates had birth weight below 2000g and 39.67% were born before 37 weeks of gestation. The cardiorespiratory signs and jaundice were the most frequent clinical features. The blood culture positivity rate was 64.87%. Klebsiella species was the commonest causative pathogen found and multidrug resistance was frequent. The overall mortality rate was 47.52% and the case fatality rate in LOS was higher than in VOS and EOS (p < 0.001). The mortality was significantly higher in neonates with lower birth weight and lower gestational age (p < 0.001). The study underlines the importance of monitoring the various features of neonatal septicemia, as well as the drug resistance of the pathogens from the nurseries.
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页码:169 / 174
页数:5
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