Rhino-orbital-cerebral mucormycosis in type 1 diabetes mellitus

被引：32

作者：

Bhadada S. ^{[1
]}

Bhansali A. ^{[1
,4
]}

Reddy K.S.S. ^{[1
]}

Bhat R.V. ^{[1
]}

Khandelwal N. ^{[2
]}

Gupta A.K. ^{[3
]}

机构：

[1] Department of Endocrinology, PGIMER, Chandigarh

[2] Department of Radiodiagnosis, PGIMER, Chandigarh

[3] Department of Otolaryngology, PGIMER, Chandigarh

[4] Department of Endocrinology, Postgraduate Institute of Medical Education and Research

来源：

The Indian Journal of Pediatrics | 2005年 / 72卷 / 8期

关键词：

Diabetes mellitus; Ketoacidosis; Mucormycosis;

D O I：

10.1007/BF02724075

中图分类号：

学科分类号：

摘要：

AIM: To describe the presentation and outcome of rhino-orbital-cerebral mucormycosis (ROCM) in adolescents with type 1 diabetes mellitus (T1DM). Methods: The medical records of six patients of T1DM with ROCM admitted between October 2001 to January 2004 were analysed. Results: The mean (± SD) age and duration of DM of these patients were 16.1 ± 3.0 years and 26.3 ± 24.9 months respectively. Four patients had ROCM at presentation, while two developed it during their hospital stay when recovering from diabetic ketoacidosis. Proptosis (100%) and ptosis (100%) were the most common symptoms, and ophthalmoplegia (85%) and vision loss (85%) were the most common signs. Maxillary sinus (85%) was the commonest paranasal sinus to be involved. All patients received amphotericin B and had appropriate surgery except one. Four patients survived. Patients who had altered sensorium, facial necrosis, palatal perforation and cerebral involvement at presentation had poor outcome. Conclusion: High index of suspicion of ROCM in T1DM and combined approach with amphotericin B and appropriate surgery is rewarding.

引用

页码：671 / 674

页数：3

共 10 条

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