Viral rhinitis.

被引:7
作者
Gentile D.A. [1 ]
Skoner D.P. [1 ]
机构
[1] Section of Allergy/Immunology, Children's Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, 15213, PA
关键词
Rhinitis; Respiratory Syncytial Virus; Allergy Clin Immunol; Zanamivir; Otitis Medium With Effusion;
D O I
10.1007/s11882-001-0009-3
中图分类号
学科分类号
摘要
Viral rhinitis is a common, morbid, and costly malady, often complicated by otitis media, sinusitis, and asthma. Current therapies are relatively ineffective and aimed at reducing symptoms rather than moderating underlying mechanisms. Nasal elevations of proinflammatory cytokines track symptom expression during viral rhinitis, and it is hypothesized that these chemicals orchestrate a common response to infection with many different viruses that cause rhinitis. Also, recent evidence supports a role for neurogenic inflammation in the development of complications. Future studies should dissect the role of proinflammatory cytokines and neuropeptides in the expression of symptoms, signs, pathophysiologies, and complications of viral rhinitis.
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页码:227 / 234
页数:7
相关论文
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