Serum immunoglobulin E in early childhood wheezing

被引：1

作者：

B. K. Das

Swati Kumar

B. K. Panda

O. P. Mishra

机构：

[1] Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi

[2] Department of Biophysics, Institute of Medical Sciences, Banaras Hindu University, Varanasi

[3] BDA Flats, Rabindrapuri Extension, B.H.U. Post Office

来源：

The Indian Journal of Pediatrics | 2003年 / 70卷 / 3期

关键词：

Bronchial asthma; Bronchiolitis; Ig E; Wheezing;

D O I：

10.1007/BF02725585

中图分类号：

学科分类号：

摘要：

Objective: To study the serum Ig E levels in patients presenting with wheezing under the age of 24 months. Methods: The study was conducted on 38 cases and 35 controls. The children presenting with first attack of wheezing were clinically considered as bronchiolitis and those with recurrent attacks with positive history of atopy in the patient or in their first degree relatives were considered as bronchial asthma. The Ig E estimation was done by immune assay method. Results: The mean serum Ig E was significantly higher in asthma patients (p<0.001). It was also higher in bronchiolitis patients but the difference was not statistically significant. However, 26 per cent of these patients had values above 1 SD of the control mean. These patients were considered as potential cases of asthma. Conclusion: The determination of serum Ig E may be of value in identifying those children presenting with first wheezing attack, who may develop asthma in future. Only a long-term follow-up of these patients can give an answer to the postulation that raised Ig E level at the time of first viral lower respiratory tract infection is a potential marker for the development of recurrent wheezing in later life.

引用

页码：213 / 215

页数：2

共 9 条

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