Cardiac troponin assays: Analytical issues and clinical reference range cutpoints

被引：14

作者：

Apple F.S. ^{[1
,2
]}

机构：

[1] Department of Laboratory Medicine and Pathology, Hennepin County Medical Center, Minneapolis, MN, 55415, 701 Park Ave.

[2] University of Minnesota School of Medicine, Minneapolis, MN, 55415, 701 Park, Ave.

来源：

Cardiovascular Toxicology | 2001年 / 1卷 / 2期

关键词：

Cardiac troponin; Immunoassay; standardization; cardiology; myocardial infarction; laboratory medicine;

D O I：

10.1385/CT:1:2:093

中图分类号：

学科分类号：

摘要：

A recently published consensus document from the European Society of Cardiology and American College of Cardiology emphasized the unique role cardiac troponin monitoring plays in redefining acute myocardial infarction. The cardiology community has now established criteria to define both the reference cutpoints and acceptable imprecision for troponin assays, which complement previous recommendations by the laboratory community. This article will review the analytical issues confronting laboratories, clinicians, and industry regarding troponin assay standardization, assay imprecision, and how clinical decision cutpoints should be established and implemented for clinical practice.

引用

页码：93 / 98

页数：5

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