Optical coherence tomography and its use in detection of vulnerable plaque

被引:5
作者
Cilingiroglu M. [1 ]
Ozer K. [1 ]
机构
[1] Department of Medicine, University of Texas Health Science Center, San Antonio, TX 78229-3900
关键词
Optical Coherence Tomography; Vulnerable Plaque; Coronary Vasculature; Plaque Characterization; Optical Coherence Tomography Signal;
D O I
10.1007/s11883-006-0051-7
中图分类号
学科分类号
摘要
Acute coronary syndromes and their associated complications related to coronary ischemia continue to be the leading cause of morbidity and mortality in the world. The most commonly encountered pathophysiologic cascade of events resulting in this picture is initiated by formation of a vulnerable plaque. Despite the widespread use of a variety of imaging technologies, high-resolution detection of the vulnerable plaque and designing a method to correlate the results of the imaging modality with disease severity and prognosis have proven to be an arduous task. The recent introduction of optical coherence tomography has proven to be an innovative contribution to the diagnostic armamentarium for the cardiologist. This article presents an overview of vulnerable plaque and methods for its imaging. It focuses on how optical coherence tomography comes into play and how it compares with other modalities in regard to plaque characterization. Copyright © 2006 by Current Science Inc.
引用
收藏
页码:140 / 143
页数:3
相关论文
共 19 条
[1]  
Yusuf S., Reddy S., Ounpuu S., Et al., Global burden of cardiovascular diseases, I: General considerations, the epidemiologic transition, risk factors, and impact of urbanization, Circulation, 104, pp. 2746-2753, (2001)
[2]  
Heart and Stroke Statistical Update, (2002)
[3]  
Falk E., Shah P.K., Fuster V., Coronary plaque disruption, Circulation, 92, pp. 657-671, (1995)
[4]  
Davies M.J., Anatomic features in victims of sudden coronary death: Coronary artery pathology, Circulation, 85, SUPPL. 1, (1992)
[5]  
Ozer K., Cilingiroglu M., Vulnerable plaque: Definition, detection, treatment and future implications, Curr Atheroscler Rep, 7, pp. 121-126, (2005)
[6]  
Brezinski M., Characterizing arterial plaque with optical coherence tomography, Curr Opin Cardiol, 17, pp. 648-655, (2002)
[7]  
Nissen S.E., Yock P., Intravascular ultrasound: Novel pathophysiological insights and current clinical applications, Circulation, 103, pp. 604-616, (2001)
[8]  
Schermund A., Baumgart D., Sack S., Et al., Assessment of coronary calcification by electron-beam computed tomography in symptomatic patients with normal, abnormal or equivocal stress test, Eur Heart J, 21, pp. 1674-1682, (2000)
[9]  
Mizuno K., Miyamoto A., Satomura K., Et al., Angioscopic coronary macromorphology in patients with acute coronary disorders, Lancet, 337, pp. 809-812, (1991)
[10]  
Casscells W., Hathorn B., David M., Et al., Thermal detection of cellular infiltrates in living atherosclerotic plaques: Possible implications for plaque rupture and thrombosis, Lancet, 347, pp. 1447-1451, (1996)