Stereotactic irradiation using a linear accelerator for brain metastasis from renal cell carcinoma

被引：10

作者：

Kawashima K. ^{[1
]}

Shirato H. ^{[1
,5
]}

Takamura A. ^{[2
]}

Shinohara N. ^{[3
]}

Sawamura Y. ^{[4
]}

Miyasaka K. ^{[1
]}

机构：

[1] Department of Radiology, Hokkaido University, School of Medicine, Sapporo

[2] Department of Radiology, Asahikawa Kousei Hospital, Hokkaido

[3] Department of Urology, Hokkaido University, School of Medicine, Sapporo

[4] Department of Neurosurgery, Hokkaido University, School of Medicine, Sapporo

[5] Department of Radiology, Hokkaido University, School of Medicine, SW1W16, Chuo-ku

来源：

International Journal of Clinical Oncology | 1997年 / 2卷 / 2期

关键词：

Brain; Metastasis; Radiotherapy; Renal cell carcinoma; Stereotactic radiosurgery;

D O I：

10.1007/BF02488876

中图分类号：

学科分类号：

摘要：

Background: The role of stereotactic irradiation using a linear accelerator for brain metastasis from renal cell carcinoma was investigated. Methods: Fifteen brain metastases in 11 patients with a history of renal cell carcinoma were treated using convergent narrow x-ray beams from a linear accelerator and rigid fixation of the head with a stereotactic frame. Twelve metastatic tumors in 8 patients were irradiated with 25 Gy at the center in a single fraction, and single tumors in 3 patients received the following doses: 25 Gy in 5 fractions, 28 Gy in 3 fractions, or 35 Gy in 4 fractions Results: The actuarial local control rate at 12 months was 90.6%. Twelve (92%) of 13 lesions that produced neurologic symptoms before stereotactic irradiation showed an improvement of symptoms. No complication related to the irradiation was observed. The median survival time was 6 months. Conclusion: Stereotactic irradiation is more effective in achieving local control than is conventional radiotherapy, and achieves improvement in symptoms and survival rates similar to those of surgical resection of the brain metastasis from renal cell carcinoma. Urologists and oncologists should be aware of the usefulness of stereotactic radiation in the management of patients with renal cell carcinoma. © JSCO/CLJ 1997.

引用

页码：73 / 76

页数：3

共 13 条

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