The effects of prenatal stress on learning in rats in a morris maze

被引：29

作者：

Aleksandrov A.A. ^{[1
]}

Polyakova O.N. ^{[1
]}

Batuev A.S. ^{[1
]}

机构：

[1] Department of Higher Nervous Activity and Psychophysiology, St. Petersburg State University, 199023 St. Petersburg

来源：

Neuroscience and Behavioral Physiology | 2001年 / 31卷 / 1期

关键词：

Learning; Morris water maze; Prenatal stress; Social stress;

D O I：

10.1023/A:1026682415860

中图分类号：

学科分类号：

摘要：

The offspring of female Wistar rats subjected to daily stress (they were placed in an unfamiliar social group for 1 h) during the last third of pregnancy were studied. The offspring of these females were tested for the ability to perform spatial orientation in a Morris water maze at the ages of two and four months. Prenatal stress had no effect on the ability of rats to learn in the Morris maze. However, two-month-old animals subjected to prenatal stress, unlike controls, demonstrated less flexibility in their behavioral strategy in solving the spatial orientation task. These animals were characterized by a clear tendency for their behavior to perseverate. By the age of four months, the differences between the control and prenatally stressed animals had disappeared.

引用

页码：71 / 74

页数：3

共 11 条

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