A new model for the origins of chronic disease.

被引：71

作者：

Barker D.J. ^{[1
]}

机构：

[1] MRC Environmental Epidemiology Unit, Southampton General Hospital, SO16 6YD, Southampton

来源：

Medicine, Health Care and Philosophy | 2001年 / 4卷 / 1期

关键词：

chronic disease; disease concept; intra-uterine life; programming;

D O I：

10.1023/A:1009934412988

中图分类号：

学科分类号：

摘要：

Living things are often plastic during their early development and are moulded by the environment. Many human fetuses have to adapt to a limited supply of nutrients, and in doing so they permanently change their physiology and metabolism. These programmed changes may be the origins of a number of diseases in later life, including coronary heart disease, stroke, diabetes and hypertension.

引用

页码：31 / 35

页数：4

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