The significance of individual resistance to hypoxia for correction of the consequences of craniocerebral trauma

被引：5

作者：

Zarubina I.V. ^{[1
]}

Shabanov P.D. ^{[1
]}

机构：

[1] Department of Pharmacology, Military Medical Academy, 194044 St. Petersburg

来源：

Neuroscience and Behavioral Physiology | 2005年 / 35卷 / 2期

关键词：

Behavior; Craniocerebral trauma; Ethomersol; Hypoxia; Metabolism; Resistance;

D O I：

10.1007/s11055-005-0016-2

中图分类号：

学科分类号：

摘要：

Experiments on rats showed that the individual resistance of the body to acute hypoxia is of decisive importance in the early recovery period after mechanical craniocerebral trauma. I.p. administration of ethomersol (25 mg/kg) during the three days following trauma decreased behavioral impairments in rats with different levels of resistance to acute hypoxia, restored the structure of individual behavior, and prevented metabolic disturbances in the brain. The results led to the conclusion that the antioxidant ethomersol is effective in hypoxia due to craniocerebral trauma. © 2005 Springer Science+Business Media, Inc.

引用

页码：215 / 219

页数：4

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