Effect of prepregnancy body mass index categories on obstetrical and neonatal outcomes

被引:199
作者
Abenhaim H.A. [1 ]
Kinch R.A. [1 ]
Morin L. [1 ]
Benjamin A. [1 ]
Usher R. [2 ]
机构
[1] Department of Obstetrics and Gynecology, McGill University, Royal Victoria Hospital, Montreal, Que. H3A 1A1, 687 Ave des Pins Ouest
[2] Department of Neonatology, McGill University, Montreal, Que.
关键词
Body mass index; Obesity; Pregnancy outcomes;
D O I
10.1007/s00404-006-0219-y
中图分类号
学科分类号
摘要
Objectives: To examine the association between body mass index (BMI) and obstetrical and neonatal outcomes. Methods: We conducted a cohort study comparing prepregnant BMI categories with obstetrical and neonatal outcomes using the McGill Obstetrical and Neonatal Database on all deliveries in 10 year period (1987-1997). Prepregnant BMI was categorized into underweight (<20), normal (20-24.9), overweight (25-29.9), obese (30-39.9), and morbidly obese (40+). Logistic regression analysis was used to adjust for age, smoking, parity, and preexisting diabetes using normal BMI as the reference. Results: The population consisted of underweight 4,312 (23.1%), normal weight 10,021 (53.8%), overweight 3,069 (16.5%), obese 1,137 (6.1%), and morbidly obese 104 (0.6%). As compared to women with normal BMIs, overweight, obese, and morbidly obese women had an increased risk of preeclampsia 2.28 (1.88-2.77), 4.65 (3.71-5.83), 6.26 (3.48-11.26); gestational hypertension 1.56 (1.35-1.81), 2.01 (1.64-2.45), 2.77 (1.60-4.78); gestational diabetes 1.89 (1.63-2.19), 3.22 (2.68-3.87), 4.71 (2.89-7.67); preterm birth 1.20 (1.04-1.38), 1.60 (1.32-1.94), 2.43 (1.46-4.05); cesarean section 1.48 (1.35-1.62), 1.85 (1.62-2.11), 2.92 (1.97-4.34); and macrosomia 1.66 (1.23-2.24), 2.32 (1.58-3.41), 2.10 (0.64-6.86). Underweight women were less likely to have: preeclampsia 0.67 (0.52-0.86), gestational hypertension 0.71 (0.60-0.83), gestational diabetes 0.82 (0.69-0.97), cesarean section 0.89 (0.81-0.97), shoulder dystocia 0.88 (0.80-0.96), birth injuries 0.40 (0.21-0.77), and macrosomia 0.43 (0.28-0.68) but more likely to have small for gestational age infants 1.54 (1.37-1.72) and intrauterine growth restricted infants 1.33 (1.07-1.67). Conclusion: In a large Canadian teaching hospital, increasing prepregnancy BMI category was associated with an increasing risk of adverse pregnancy outcomes. Underweight prepregnancy BMI was associated with a reduced risk of adverse pregnancy outcomes. © 2006 Springer-Verlag.
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页码:39 / 43
页数:4
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共 17 条
  • [1] Wilding J., Science, medicine, and the future: Obesity treatment, BMJ, 315, pp. 997-1000, (1997)
  • [2] Jung R.T., Obesity as a disease, Br Med Bull, 53, pp. 307-321, (1997)
  • [3] Allison D.B., Saunders S.E., Obesity in North America: An overview, Med Clin North Am, 84, pp. 305-332, (2000)
  • [4] Bianco A.T., Smilen S.W., Davis Y., Lopez S., Lapinski R., Lockwood C.J., Pregnancy outcome and weight gain recommendations for the morbidly obese women, Obstet Gynecol, 97, pp. 97-102, (1998)
  • [5] De Groot L.C., High maternal body weight and pregnancy outcome, Nutr Rev, 57, pp. 62-64, (1999)
  • [6] Sebire N.J., Is maternal underweight really a risk factor for adverse pregnancy outcome? A population-based study in London, BJOG, 108, pp. 61-66, (2001)
  • [7] Cnattingius S., Bergstrom R., Lipworth L., Kramer M.S., Prepregnancy weight and the risk of adverse pregnancy outcomes, N Engl J Med, 338, pp. 147-152, (1998)
  • [8] Bowers J., Obesity and related pregnancy complications in an inner-city clinic, J Perinatol, 19, pp. 216-219, (1999)
  • [9] Michlin R., Maternal obesity and pregnancy outcome, Isr Med Assoc J, 2, pp. 10-13, (2000)
  • [10] Usher R., McLean F., Intrauterine growth of live born Caucasian infants at sea level