Acinic cell adenocarcinoma arising in the breast of a young male: A clinicopathological, immunohistochemical and ultrastructural study

被引:20
作者
Shimao K. [1 ]
Haga S. [1 ]
Shimizu T. [1 ]
Imamura H. [1 ]
Watanabe O. [1 ]
Kinoshita J. [1 ]
Nagumo H. [1 ]
Utada Y. [1 ]
Okabe T. [1 ]
Kajiwara T. [1 ]
Oshibe N. [1 ,2 ]
Aiba M. [2 ]
机构
[1] Department of Surgery, Tokyo Women's Medical College, Daini Hospital, Arakawa-ku, Tokyo 116, 2-1-10, Nishiogu
[2] Department of Surgical Pathology, Tokyo Women's Medical College, Daini Hospital
关键词
Acinic cell adenocarcinoma; Breast; Immunohistochemistry; Salivary-type amylase; Ultrastructure;
D O I
10.1007/BF02967419
中图分类号
学科分类号
摘要
A 23-year-old man with acinic cell adenocarcinoma of the breast is reported. He presented with a 4.8×4.2 cm mass in his left breast, and excisional biopsy was performed. Under the light microscope, tumor cells had abundant periodic acid-Schiff-positive secretory granules and eosinophilic cytoplasms. Electron microscopy revealed the granules to have various electron densities, a finding characteristic of acinic cell adenocarcinoma. Immunohistochemically, the tumor cells were stained with salivary-type amylase. Electron microscopic and immunohistochemical investigation greatly facilitated the diagnosis of this acinic cell adenocarcinoma, which was in an unusual location. We believe this is the first case report of acinic cell adenocarcinoma of the mammary gland studied utilizing light microscopic, ultrastructural and immunohistochemical techniques.
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页码:77 / 81
页数:4
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