Three-year (1999-2002) of epidemiological and virological surveillance of influenza in north-east Italy

被引：7

作者：

Ansaldi F. ^{[1
]}

D'Agaro P. ^{[1
]}

Burgnich P. ^{[1
]}

De Florentiis D. ^{[1
]}

Favero S. ^{[1
]}

Dal Molin G. ^{[1
]}

Comar M. ^{[1
]}

Coppola N. ^{[2
]}

Campello C. ^{[1
,3
]}

机构：

[1] Department of Public Medicine Sciences, U.C.O. Hygiene and Preventive Medicine, University of Trieste, Trieste

[2] Direzione Regionale Della Sanità e Delle Politiche Sociali, Friuli-Venezia Giulia Region

[3] Department of Public Medicine Sciences, U.C.O. Hygiene and Preventive Medicine, IRCCS Burlo Garofolo, 34100 Trieste

来源：

European Journal of Epidemiology | 2004年 / 19卷 / 9期

关键词：

Epidemiology; Influenza; Virological surveillance;

D O I：

10.1023/B:EJEP.0000040529.60673.b7

中图分类号：

学科分类号：

摘要：

The results of the epidemiological and virological surveillance of influenza performed during the 1999/2000, 2000/2001 and 2001/2002 seasons in the northeastern Italy were presented and the relationship between age-specific morbidity rates and circulating strains were discussed.The epidemiological findings pointed out a change in age distribution. During the 1999/2000 season, characterized by a circulation of viruses antigenically close to the vaccine strain, a similar incidence rate in the 0-14 and 15-64-year-old groups was observed, while during the 2001/2002 winter the virus infected mostly children. During 2001/2002 season, B type viruses predominated with at least three distinguishable molecular variants. In particular, B/Victoria/2/87-like viruses re-emerged after more than a decade, and the antibodies elicited by the vaccine strain and by the strains circulating in previous seasons were poor or not protecting. The accumulation of susceptible subjects in young age group during the 1990s, due to the lack of circulation of B/Victoria/2/87-like viruses, was responsible for the unusual morbidity in the 0-14 year group. No circulation of B/Victoria/2/87-like viruses was observed in >64-year-old group during 2001/2002 epidemic, probably due to a long-lasting immunity against viruses belonging to this lineage. © 2004 Kluwer Academic Publishers.

引用

页码：885 / 890

页数：5

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