THE VERIFICATION OF AN INVERSE PROBLEM IN RADIATION-THERAPY

被引:15
作者
KOOY, HM [1 ]
BARTH, NH [1 ]
机构
[1] HARVARD UNIV,SCH MED,DEPT RADIAT THERAPY,BOSTON,MA 02115
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1990年 / 18卷 / 02期
关键词
Inverse problem; Optimization; Photons; Treatment planning;
D O I
10.1016/0360-3016(90)90112-W
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The inverse problem in radiation therapy presents a solution for a fluence distribution based on the specification of a region of dose in a patient. We show results for one such solution based on the inversion of an integral over a function of the fluence profile of a rotating beam. We use Monte Carlo methods and numerical integrations to evaluate dose distributions obtained with the inverse method and show the limitations of this theoretical approach. Our results show that dose to a single circular region at an arbitrary position in a 2-dimensional volume can be calculated. Uniform dose to arbitrarily shaped regions cannot be calculated with this formalism, although practical solutions can still be obtained. © 1990.
引用
收藏
页码:433 / 439
页数:7
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