THE CIRCADIAN SYSTEM AND AFFECTIVE-DISORDERS - CLOCKS OR RHYTHMS

被引：23

作者：

HEALY, D

WATERHOUSE, JM

机构：

[1] Department of Psychiatry, University of Cambridge Clinical School, Cambridge

[2] Department of Physiology, University of Manchester, Manchester

来源：

CHRONOBIOLOGY INTERNATIONAL | 1990年 / 7卷 / 01期

关键词：

Depression; Key words-Circadian clocks; Mania; Social dislocation; Social zeitgebers;

D O I：

10.3109/07420529009056947

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

There have been a number of proposals that a pathology of the circadian system involving clock functioning underlies the affective disorders. It is argued that neither current findings from research into the neurophysiological substrates of the affective disorders, recent clinical findings regarding these illnesses or their phenomenology support such a contention. This does not mean however that there is not a primary pathological disturbance of the circadian system at the heart of the affective disorders. The same neurophysiological, phenomenological and clinical evidence can be offered in favour of a disturbance of circadian rhythms in the presence of grossly normal clock functioning. The research and remedial implications of this alternative are outlined briefly. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：5 / 10

页数：6

共 20 条

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