ANALYSES OF MONOCLONAL-ANTIBODIES REACTIVE WITH PORCINE CD6

被引：22

作者：

SAALMULLER, A

AASTED, B

CANALS, A

DOMINGUEZ, J

GOLDMAN, T

LUNNEY, JK

MAURER, S

PAULY, T

PESCOVITZ, MD

POSPISIL, R

SALMON, H

TREBICHAVSKY, I

VALPOTIC, I

VIZCAINO, JS

WEILAND, E

ZUCKERMANN, F

机构：

[1] ROYAL VET & AGR UNIV, DEPT VET VIROL & IMMUNOL, DK-1870 FREDERIKSBERG C, DENMARK

[2] INIA, DEPT SANIDAD ANIM, E-28012 MADRID, SPAIN

[3] USDA ARS, HELMINTH DIS LAB, BELTSVILLE, MD 20705 USA

[4] INDIANA UNIV, DEPT SURG & MICROBIOL IMMUNOL, INDIANAPOLIS, IN 46202 USA

[5] ACAD SCI CZECH REPUBL, INST MICROBIOL, DEPT IMMUNOL, CR-14220 PRAGUE, CZECH REPUBLIC

[6] INRA, IMMUNOL LAB, F-37380 MONNAIE, FRANCE

[7] UNIV ZAGREB, FAC VET, DEPT BIOL, ZAGREB 41000, CROATIA

[8] UNIV ILLINOIS, COLL VET MED, DEPT VET PATHOBIOL, URBANA, IL 61801 USA

来源：

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY | 1994年 / 43卷 / 1-3期

关键词：

D O I：

10.1016/0165-2427(94)90143-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Amongst the monoclonal antibodies (mAbs) submitted to the first porcine CD workshop, two mAbs (workshop numbers 055 and 120) could be identified to recognize the porcine CD6 analogue. Both mAbs seemed to be highly T-cell specific and showed neither reactivity with cells of the myeloic lineage nor with B lymphocytes. The observed molecular mass of the antigen precipitated by mAb 120 of 110 kDa confirmed this classification. Without molecular analyses of the antigen recognized by mAb 055, but similar staining pattern in FCM compared with 120, mAb 055 was allocated to the wCD6 subcluster.

引用

页码：243 / 247

页数：5

共 7 条

[1]

BALDWIN CL, 1988, IMMUNOLOGY, V63, P439

[2] THE CLUSTERS OF DIFFERENTIATION (CD) DEFINED BY THE 1ST INTERNATIONAL WORKSHOP ON HUMAN-LEUKOCYTE DIFFERENTIATION ANTIGENS [J].